Results 81 to 90 of about 947,912 (287)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Spectral Control via Multi-Species Effects in PW-Class Laser-Ion Acceleration [PDF]

, 1996
Laser-ion acceleration with ultra-short pulse, PW-class lasers is dominated by non-thermal, intra-pulse plasma dynamics. The presence of multiple ion species or multiple charge states in targets leads to characteristic modulations and even mono-energetic
Huebl, Axel, Rehwald, Martin, Obst-Huebl, Lieselotte, Ziegler, Tim, Garten, Marco, Widera, René, Zeil, Karl, Cowan, Thomas E., Bussmann, Michael, Schramm, Ulrich, Kluge, Thomas   +10 more
core   +5 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Robust Model-Free Fault-Tolerant Predictive Control for PMSM Drive System

IEEE Access
The parameter mismatch caused by the parameter uncertainties and unknown disturbances degrades the performance of finite-control-set model predictive control (FCS-MPC).
Shu Cheng, Ruirui Zhou, Zhuoxin Li, Zhen Xi, Jundong Zhao, Kaihui Zhao, Chaoqun Xiang   +6 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Etude préliminaire d'une commande sans modèle pour papillon de moteur [PDF]

, 2008
International audienceNew techniques of "model-free control'' are applied to throttles, which are valves that directly regulate the amount of air entering the engines.
Fliess, Michel, Join, Cédric, Masse, John   +2 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Observer-based event-triggered model-free adaptive sliding mode predictive control

Journal of Applied Science and Engineering
For simple-input and simple-output (SISO) discrete-time nonlinear systems, an observer-based event-triggered model-free adaptive sliding mode predictive control technique (EMFASPC) is put forth in this study.
Bing Ren, Guangqing Bao
doaj   +1 more source

Synthetic learner: model-free inference on treatments over time

, 2019
Understanding of the effect of a particular treatment or a policy pertains to many areas of interest -- ranging from political economics, marketing to health-care and personalized treatment studies.
Bradic, Jelena, Viviano, Davide
core  

Predictive Control for Alleviation of Gust Loads on Very Flexible Aircraft

, 2014
In this work the dynamics of very flexible aircraft are described by a set of non-linear, multi-disciplinary equations of motion. Primary structural components are represented by a geometrically-exact composite beam model which captures the large dynamic
Chen P., Goland M., Goland M., Géradin M., Géradin M., Maciejowski J. M., Rawlings J. B., Simpson R. J. S., Stevens B. L.   +8 more
core   +1 more source