Results 91 to 100 of about 35,199,249 (362)
Second Symposium on Chemical Evolution and the Origin of Life [PDF]
Recent findings by NASA Exobiology investigators are reported. Scientific papers are presented in the following areas: cosmic evolution of biogenic compounds, prebiotic evolution (planetary and molecular), early evolution of life (biological and ...
Devincenzi, D. L., model.
core +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Model-driven description and validation of composite learning content [PDF]
, 2010 Authoring of learning content for courseware systems is a complex activity requiring the combination of a range of design and validation techniques. We introduce the CAVIAr courseware models allowing for learning content description and validation. Model-
Melia, Mark, Pahl, Claus
core +1 more source
Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A
Scientific Reports, 2017 Hedgehog (Hh) signaling plays a pivotal role in animal development and its deregulation in humans causes birth defects and several types of cancer. Protein Kinase A (PKA) modulates Hh signaling activity through phosphorylating the transcription factor ...
Ping Chen +7 more
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Picture Word Inductive Model Effective Research as the Media for Increasing Students' Writing Aility in Descriptive Text [PDF]
, 2018 Tujuan penelitian ini adalah untuk mengetahui apakah siswa yang diajar dengan picture word inductive model memiliki keterampilan menulis teks deskriptif lebih baik dari pada siswa yang diajar dengan gambar biasa.
Yulizar, Y. (Yulizar)
core
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
Towards a New Model of Leadership for the NHS [PDF]
, 2013 This paper was commissioned by the NHS Leadership Academy as a contribution to thinking about the future development of leadership in and around the NHS. It was prepared in collaboration with the Hay Group.
Holti, Richard, Storey, John
core
Comparing Poisson Sigma Model with A-model [PDF]
, 2016 We discuss the A-model as a gauge fixing of the Poisson Sigma Model with target a symplectic structure. We complete the discussion in [arXiv:0706.3164], where a gauge fixing defined by a compatible complex structure was introduced, by showing how to ...
Bonechi, Francesco +2 more
core +3 more sources
HAX1 inhibits apoptosis and promotes maturation of neutrophils
Cell Communication and SignalingAs the diverse functions of neutrophils continue to be uncovered, elucidating the molecular mechanisms that regulate their differentiation, development, and apoptosis has become crucial for overcoming limitations in the treatment of neutrophil-related ...
Hanwei Yue +4 more
doaj +1 more source