Results 141 to 150 of about 1,202,565 (290)

Bayesian Model Averaging for Model Implied Instrumental Variable Two Stage Least Squares Estimators

, 2018
Model-Implied Instrumental Variable Two-Stage Least Squares (MIIV-2SLS) is a limited information, equation-by-equation, non-iterative estimator for latent variable models.
Bollen, Kenneth A., Fisher, Zachary F., Henry, Teague R.   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

An Efficient Quasi‐Monte Carlo Method for Concurrent Estimation of First‐Order and Total‐Effect Process Sensitivity Indices

Water Resources Research
Developing and improving process‐based models requires identifying the importance and/or influence of various processes driving system behavior. In our recent studies, important processes are identified using first‐order process sensitivity index PSK ...
Jing Yang, Ming Ye, Alberto Guadagnini, Heng Dai, Tian Jiao   +4 more
doaj   +1 more source

Bayesian multiregional clinical trials using model averaging. [PDF]

Biostatistics, 2023
Bean NW, Ibrahim JG, Psioda MA.
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Forecasting Pathogen Dynamics with Bayesian Model-Averaging: Application to Xylella fastidiosa. [PDF]

Bull Math Biol, 2023
Abboud C, Parent E, Bonnefon O, Soubeyrand S.   +3 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Bayesian model averaging for predicting factors associated with length of COVID-19 hospitalization. [PDF]

BMC Med Res Methodol, 2023
Bahrami S, Hajian-Tilaki K, Bayani M, Chehrazi M, Mohamadi-Pirouz Z, Amoozadeh A.   +5 more
europepmc   +1 more source

Bayesian model averaging

, 2009
Συχνά στην ανάλυση δεδομένων αποφεύγουμε (ηθελημένα ή μη) να αναφέρουμε την αβεβαιότητα την οποία περιέχει η επιλογή ενός μοντέλου. Αυτή η πηγή αβεβαιότητας όμως είναι αρκετά σημαντική όταν ενδιαφερόμαστε για πρόβλεψη κάποιας ποσότητας (π.χ. μιας νέας παρατήρησης, του κόστους μιας απόφασης). Μια μέθοδος αντιμετώπισης του προβλήματος είναι η σταθμισμένη
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source