Results 51 to 60 of about 775,103 (306)

Toward Conceptual Analysis of Cyber-Physical Systems Projects Focusing on the Composition of Legacy Systems

IEEE Access, 2023
The increase in connectivity and the continued need to evolve existing systems impose on system engineers the reality of dealing with System of Systems (SoS) concept in practice.
Andre A. S. Ivo, Sheila Granato Ribeiro, Fatima Mattiello-Francisco, Andrea Bondavalli   +3 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Automated Piping in an Airbus A320 Landing Gear Bay Using Graph-Based Design Languages

Aerospace, 2022
System design in an aircraft is still a costly, manual and iterative approach. One major cost driver of changes in system installation are design efforts for creating new pipes in an earlier stage and the costs accumulated during the in service life.
Moritz Neumaier, Stefan Kranemann, Bernd Kazmeier, Stephan Rudolph   +3 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Characterizing Efficacy of Alternative Media for Requirements Expression

Systems
Requirements are most commonly expressed in natural language, but alternative media can be employed. Previous research has established the viability of model diagrams and engineering drawings for requirements expression.
Jason Kolligs, Lawrence Dale Thomas
doaj   +1 more source

Bibliometric analysis of model-based systems engineering in advanced manufacturing [PDF]

Journal of Intelligent Manufacturing and Special Equipment
Purpose – Model-based systems engineering (MBSE) is an important approach for the transforming process from “document-centered” to “model centered” systems engineering mode in equipment development, which can effectively shorten the equipment development
Jinzhi Lu, Yihui Gong, Guoxin Wang, Yan Yan   +3 more
doaj   +1 more source

Model Signatures for the Integration of Simulation Models into System Models

Systems, 2022
Model-based systems engineering (MBSE) is an auspicious approach to the virtual development of cyber-physical systems. The behavior of the system’s elements is thus represented by specialized simulation models that are integrated into the descriptive ...
Thilo Zerwas, Georg Jacobs, Julia Kowalski, Stephan Husung, Detlef Gerhard, Bernhard Rumpe, Klaus Zeman, Seyedmohammad Vafaei, Florian König, Gregor Höpfner   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Quantitative Set-Based Design to Inform Design Teams

Applied Sciences, 2021
System designers, analysts, and engineers use various techniques to develop complex systems. A traditional design approach, point-based design (PBD), uses system decomposition and modeling, simulation, optimization, and analysis to find and compare ...
Eric Specking, Nicholas Shallcross, Gregory S. Parnell, Edward Pohl   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source