Results 71 to 80 of about 235,774 (263)

Usability evaluation of the domain specific language for spatial simulation scenarios

Cogent Engineering, 2018
This article presents the results of a usability evaluation initiative conducted on the Domain Specific Language for Spatial Simulation Scenarios (short name DSL3S) and its supporting tools.
Luís Moreira de Sousa, Alberto Rodrigues da Silva   +1 more
doaj   +1 more source

Language Architecture: An Architecture Language for Model-Driven Engineering

Proceedings of the 5th International Conference on Model-Driven Engineering and Software Development, 2017
The increasing number of languages used to engineer complex systems causes challenges to the development and maintenance processes of these languages. In this paper, we reflect on our experience in developing real life complex cyber-physical systems by using MDE techniques and DSLs.
Niels Brouwers, Marc Hamilton, Ivan Kurtev, Yaping Luo   +3 more
openaire   +2 more sources

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Model driven architecture and ontology development. [PDF]

, 2006
Defining a formal domain ontology is generally considered a useful, not to say necessary step in almost every software project. This is because software deals with ideas rather than with self-evident physical artefacts. However, this development step is hardly ever done, as ontologies rely on well-defined and semantically powerful AI concepts such as ...
Gašević, D., Đurić, Dragan, Devedžić, Vladan   +2 more
openaire  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Model-Driven Analysis towards Interoperability of Assessments in LMS

Journal of Information and Organizational Sciences, 2010
In this article we are focusing on interoperability of two aspects of LMS systems - test question types and assessments as such. The proposed strategy is based on MDA, especially on the Platform Independent Models (PIM).
Zuzana Bizonova, Katarina Pilatova
doaj  

Model-Driven Architecture for Accelerating the Development of Tourism Applications

IEEE Access
The tourism sector has witnessed a significant shift towards digital transformation, with mobile and web applications becoming essential tools for enhancing tourist experiences.
Lahbib Naimi, Lamya Benaddi, Charaf Ouaddi, Adnane Souha, Hamza Abdelmalek, Abdeslam Jakimi   +5 more
doaj   +1 more source

Obtaining and Visualization of the Topological Functioning Model from the UML Model

Applied Computer Systems, 2015
A domain model can provide compact information about its corresponding software system for business people. If the software system exists without its domain model and documentation it is time-consuming to understand its behavior and structure only from ...
Ovchinnikova Viktoria
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Model Driven Architecture (MDA): Integration and Model Reuse for Open Source eLearning Platforms

E-learning and Education, 2005
Open Source (OS) community offers numerous eLearning platforms of both types: Learning Management Systems (LMS) and Learning Content Systems (LCS). General purpose OS intermediaries such as SourceForge, ObjectWeb, Apache or specialized intermediaries ...
Blasius Lofi Dewanto, Frank Bensberg, Heinz Lothar Grob   +2 more
doaj