Results 81 to 90 of about 20,578 (261)

Model driven distribution pattern design for dynamic web service compositions [PDF]

open access: yes, 2006
Web service compositions are often used to realise servicebased enterprise applications. These enterprise systems are built from many existing discrete applications, often legacy applications exposed using Web service interfaces.
Patcas, Lucian   +7 more
core   +1 more source

Enabling End-to-End Orchestration of Multi-Cloud Applications

open access: yesIEEE Access, 2017
The orchestration of application components across heterogeneous cloud providers is a problem that has been tackled using various approaches, some of which led to the creation of cloud orchestration and management standards, such as TOSCA and CAMP ...
Kena Alexander   +3 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Studium badawcze projektu implementacji szkoły zasobowej

open access: yesActa Universitatis Lodziensis. Folia Oeconomica
Artykuł opisuje oryginalny projekt implementacji systemu szkoły zasobowej. Celem publikacji jest przedstawienie wyników badań empirycznych wynikających z realizacji tego projektu w środowisku akademickim.
Artur Machura
doaj   +1 more source

ASPECTS REGARDING THE INTEGRATION OF THE MODERN INFORMATION SYSTEMS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2010
Developing an information system integration strategy, at enterprise level is one of the most difficult issues that the information systems managers must solve, within the present conditions.
Botezatu Cornelia Paulina   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Customisable transformation-driven evolution for service architectures [PDF]

open access: yes, 2011
Service-based architectures have now become commonplace, creating the need to address their systematic maintenance and evolution. We propose to enable transformation-driven evolution for service architectures in a semi-automated fashion.
Aakash, Ahmad   +5 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Semantic model-driven development of service-centric software architectures [PDF]

open access: yes, 2007
Service-oriented architecture (SOA) is a recent architectural paradigm that has received much attention. The prevalent focus on platforms such as Web services, however, needs to be complemented by appropriate software engineering methods.
Pahl, Claus, Barrett, Ronan
core  

Relationships between UML Sequence Diagrams and the Topological Functioning Model for Backward Transformation

open access: yesApplied Computer Systems, 2014
The software system needs to be analyzed and designed before the program code is written. A Computation Independent Model (CIM) and a Platform Independent Model/ Platform Specific Model (PIM/PSM) from Model-Driven Architecture (MDA) will be partially ...
Ovchinnikova Viktoria   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy