Results 91 to 100 of about 11,068 (304)

Model-Driven Architecture for Accelerating the Development of Tourism Applications

IEEE Access
The tourism sector has witnessed a significant shift towards digital transformation, with mobile and web applications becoming essential tools for enhancing tourist experiences.
Lahbib Naimi, Lamya Benaddi, Charaf Ouaddi, Adnane Souha, Hamza Abdelmalek, Abdeslam Jakimi   +5 more
doaj   +1 more source

Museum Space – Model-driven Web-based Platform for Digitalisation and Preservation of Cultural Heritage

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2018
Museum Space is an end-to-end Museum Management Software Suite developed to help Galleries, Libraries, Archives, and Museums (GLAM) make the World’s Cultural Treasure accessible to and meaningful for all.
Maria Todorova, Teodor Martev
doaj   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

User Oriented Approach in Information Communication Technology Research

Communications, 2017
User-oriented approach is changing the way of information systems development and affects the processes, methodologies and paradigms proposed by software architects and developers.
Zuzana Juchova Juroskova, Boris Bucko
doaj   +1 more source

Semantic model-driven development of service-centric software architectures [PDF]

, 2007
Service-oriented architecture (SOA) is a recent architectural paradigm that has received much attention. The prevalent focus on platforms such as Web services, however, needs to be complemented by appropriate software engineering methods.
Pahl, Claus, Barrett, Ronan
core  

Mapping EDOC to Web Services using YATL [PDF]

, 2004
Modeling is a technique used extensively in industry to define software systems, the UML being the most prominent example. With the increased use of modeling techniques has come the desire to use model transformations.
Patrascoiu, Octavian
core   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Poole -- Model-Driven Architecture. ECOOP 2001.

, 2001
This paper surveys the core OMG MDA standards (i.e., UML, MOF, XMI and CWM) and discusses the current attempts at mapping these standards to J2EE, as examples of PIM-to-PSM translations that are currently under development.
John D. Poole, Model-Driven Architecture Vision   +1 more
core  

Semi-automatic distribution pattern modeling of web service compositions using semantics [PDF]

, 2006
Enterprise systems are frequently built by combining a number of discrete Web services together, a process termed composition. There are a number of architectural configurations or distribution patterns, which express how a composed system is to be ...
Ronan Barrett, Claus Pahl, Pahl, Claus, Barrett, Ronan   +3 more
core   +1 more source