Results 61 to 70 of about 11,068 (304)

Generating Accessible Webpages from Models

Computers
Despite significant efforts to promote web accessibility through the adoption of various standards and tools, the web remains inaccessible to many users.
Karla Ordoñez-Briceño, José R. Hilera, Luis De-Marcos, Rodrigo Saraguro-Bravo   +3 more
doaj   +1 more source

Flexible Implantable Silicon Carbide Multi‐Electrode Array (MEA) for Cell Multichannel Recording and Cell Ablation

Advanced Materials Technologies, EarlyView.
Flexible silicon carbide (SiC) microelectrode arrays enable high‐fidelity, multichannel cell extracellular recording and precise localized ablation. SiC has been extensively evaluated to persist long‐term in chronic physiological conditions while remaining robust, with excellent electrical and electrochemical stability.
Minh Anh Huynh, Matthew Barton, Sharda Yadav, Tuan‐Khoa Nguyen, Nam‐Trung Nguyen   +4 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

BlockASP: A Framework for AOP-Based Model Checking Blockchain System

IEEE Access, 2023
Blockchain systems are lauded for their security, and reliability. Security is a cornerstone, as they employ cryptographic techniques to ensure the immutability of data, making it extremely resistant to tampering.
Anas M. R. AlSobeh, Aws A. Magableh
doaj   +1 more source

Model driven distribution pattern design for dynamic web service compositions [PDF]

, 2006
Web service compositions are often used to realise servicebased enterprise applications. These enterprise systems are built from many existing discrete applications, often legacy applications exposed using Web service interfaces.
Patcas, Lucian, Lucian M. Patcas, Ronan Barrett, Murphy, John, Claus Pahl, John Murphy, Pahl, Claus, Barrett, Ronan   +7 more
core   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Modelinės architektūros naudojimas kuriant komponentines programų sistemas

Informacijos Mokslai, 2009
Modelinė architektūra gana paplitusi, tačiau jos taikymai komponentinei paradigmai yra tik daliniai – neatsižvelgiama į reikalavimą atskirti komponentų ir komponentinių sistemų kūrimo procesus.
Vaidas Giedrimas
doaj   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

Pattern-Based Coarse-Grained Component Modelling for Enterprise Application Software Developing

MATEC Web of Conferences, 2016
To improve the efficiency of ESA (Enterprise Application Software) development, component-based software development is a good solution. However, though those general software components, like JavaBean, COM/COM+ (Component Object Model), are maturely ...
Li Hai Bo, Liang Meng Xia, Gao Ya Feng
doaj   +1 more source