Results 51 to 60 of about 1,030,481 (267)
Towards Realistic Industrial Anomaly Detection: MADE-Net Framework and ManuDefect-21 Benchmark
Applied SciencesVisual anomaly detection (VAD) plays a critical role in manufacturing and quality inspection, where the scarcity of anomalous samples poses challenges for developing reliable models.
Junyang Yang, Jiuxin Cao, Chengge Duan
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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Enterprise Modelling and Integration [PDF]
, 2003 Enterprise Modelling and Integration has evolved over the last decades from entity-relationship and activity modelling to object and flow modelling as well as from pier-to-pier system integration to inter-organisational exchanges enabling various forms of electronic commerce. The next challenge is Enterprise Interoperability, i.e.
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Integrative Modelling of Biomolecular Complexes
Journal of Molecular Biology, 2020 In recent years, the use of integrative, information-driven computational approaches for modeling the structure of biomolecules has been increasing in popularity. These are now recognized as a crucial complement to experimental structural biology techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy and cryo-electron ...
Koukos, P.I., Bonvin, A.M.J.J.
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BMC Oral Health, 2022 Background Lip and oral cavity cancer has been reported as the 10th most common cancer in Thailand. Recently, a screening program for oral potentially malignant disorders (OPMDs) and oral cancer was conducted in the northeastern Thailand which took into ...
Boworn Klongnoi +7 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Integrability in sigma-models [PDF]
, 2019 Abstract The following topics are covered in this chapter: (1) Homogeneous spaces, (2) Classical integrability of sigma-models in two dimensions, (3) Topological terms, (4) Background-field method and beta-function, (5) S-matrix bootstrap in the O(N) model, (6) Supersymmetric coset models and strings on AdS(d) x X.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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