Results 71 to 80 of about 729,060 (268)
Automated deep-learning model optimization framework for microcontrollers
This paper introduces a framework for optimizing deep-learning models on microcontrollers (MCUs) that is crucial in today’s expanding embedded device market. We focus on model optimization techniques, particularly pruning and quantization, to enhance the
Seungtae Hong, Gunju Park, Jeong-Si Kim
doaj +1 more source
With the advancement of artificial intelligence, deep learning has become instrumental in land cover classification. While there has been a notable emphasis on refining model structures to improve classification accuracy, it is imperative to also ...
Yichuan Li +6 more
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The PDB_REDO server for macromolecular structure model optimization
The refinement and validation of a crystallographic structure model is the last step before the coordinates and the associated data are submitted to the Protein Data Bank (PDB).
Robbie P. Joosten +3 more
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
MaizeStar-YOLO: Precise Detection and Localization of Seedling-Stage Maize
Efficient detection and localization of maize seedlings in complex field environments is essential for accurate plant segmentation and subsequent three-dimensional morphological reconstruction. To overcome the limited accuracy and high computational cost
Taotao Chu +6 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Wind power prediction is essential for ensuring the stability and efficient operation of modern power systems, particularly as renewable energy integration continues to expand.
Zongxu Liu +3 more
doaj +1 more source

