Results 81 to 90 of about 1,079,572 (317)

Predicting the Potential Distribution of Aconitum carmichaelii Debeaux in China Under Climate Change Using an Optimized MaxEnt Model

Plants
Aconitum carmichaelii Debeaux has been a traditional medicinal resource in China for over two millennia. However, sustainable utilization and preservation strategies for A.
Jieru Chen, Wei Zhang, Shimeng Cui, Xinyue Zhu, Yangyang Chen, Jingyuan Ren, Ziling Liu, Yiqiong Liu, Hai Liao, Jiayu Zhou   +9 more
doaj   +1 more source

Optimized Particle Swarm Optimization (OPSO) and its application to artificial neural network training

, 2006
Background: Particle Swarm Optimization (PSO) is an established method for parameter optimization. It represents a population-based adaptive optimization technique that is influenced by several "strategy parameters".
Meissner, Michael, Michael Schmuker (4736406), Schmuker Michael, Schneider, Gisbert (Prof. Dr.), Michael Meissner, Michael Schmuker, Gisbert Schneider, Schmuker, Michael, Gisbert Schneider (17096), Meissner Michael, Schneider Gisbert, Michael Meissner (17094)   +11 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Automated deep-learning model optimization framework for microcontrollers

ETRI Journal
This paper introduces a framework for optimizing deep-learning models on microcontrollers (MCUs) that is crucial in today’s expanding embedded device market. We focus on model optimization techniques, particularly pruning and quantization, to enhance the
Seungtae Hong, Gunju Park, Jeong-Si Kim
doaj   +1 more source

Research on the Optimization of Multi-Class Land Cover Classification Using Deep Learning with Multispectral Images

Land
With the advancement of artificial intelligence, deep learning has become instrumental in land cover classification. While there has been a notable emphasis on refining model structures to improve classification accuracy, it is imperative to also ...
Yichuan Li, Junchuan Yu, Ming Wang, Minying Xie, Laidian Xi, Yunxuan Pang, Changhong Hou   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The PDB_REDO server for macromolecular structure model optimization

IUCrJ, 2014
The refinement and validation of a crystallographic structure model is the last step before the coordinates and the associated data are submitted to the Protein Data Bank (PDB).
Robbie P. Joosten, Fei Long, Garib N. Murshudov, Anastassis Perrakis   +3 more
doaj   +1 more source

Strong Equivalence of Qualitative Optimization Problems

, 2012
We introduce the framework of qualitative optimization problems (or, simply, optimization problems) to represent preference theories. The formalism uses separate modules to describe the space of outcomes to be compared (the generator) and the preferences
Stefan Woltran, Truszczyński, Miroslaw, Woltran, Stefan, Faber, Wolfgang, Miroslaw Truszczynski, Wolfgang Faber   +5 more
core  

Learning-based ship design optimization approach

, 2012
With the development of computer applications in ship design, optimization, as a powerful approach, has been widely used in the design and analysis process.
Philip Sayer, Osman Turan, Turan, Osman, Cui, Hao, Sayer, Philip, Hao Cui   +5 more
core   +1 more source