Results 131 to 140 of about 1,373,381 (258)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tillil J, Huisinga W, Knöchel J.
europepmc   +1 more source

Simultaneous normal form transformation and model-order reduction for systems of coupled nonlinear oscillators. [PDF]

Proc Math Phys Eng Sci, 2019
Liu X, Wagg DJ.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Model Order Reduction by Legendre Expansion Using Harmony Search Algorithm

Majlesi Journal of Electrical Engineering
In this paper, a new approach is investigated for order reduction based on Legendre expansion. Harmony Search is used in this approach, to determine the reduced order model's parameters. The Routh criterion is applied to specify the stability conditions.
Hasan Nasiri Soloklo, Malihe Maghfoori Farsangi   +1 more
doaj  

Two-Phase Approach for Fast Topology Optimization of Multi-Resonant MEMS Involving Model Order Reduction. [PDF]

Micromachines (Basel)
Hu S, Manansala B, Fitzer U, Hohlfeld D, Bechtold T.   +4 more
europepmc   +1 more source

Genetic Algorithm-Based Model Order Reduction of Aeroservoelastic Systems with Consistent States. [PDF]

J Aircr, 2017
Zhu J, Wang Y, Pant K, Suh PM, Brenner MJ.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A new model order reduction strategy adapted to nonlinear problems in earthquake engineering. [PDF]

Earthq Eng Struct Dyn, 2017
Bamer F, Amiri AK, Bucher C.
europepmc   +1 more source