Results 111 to 120 of about 4,816,952 (284)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A Forecast Test for Reducing Dynamical Dimensionality of Model Emulators

Journal of Advances in Modeling Earth Systems
The climate system can be numerically represented by a set of physically based dynamical equations whose solution requires substantial computational resources.
Tongtong Xu, Matthew Newman, Michael A. Alexander, Antonietta Capotondi   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Model Order Reduction of Vehicle Air-Conditioning Loop with Neural Networks

Engineering Perspective
To meet the energy demand, passenger’s comfort and sustainability in the air conditioning system of vehicles, the Neural Network plays an intelligent role. In this study, the vehicle air conditioning loop was replaced with the reduced control model using
Dr. Shıvakumar Nagareddy, Ravi Subramanyam, Vijay Govindarasu, Veeramani Neelakandan   +3 more
doaj   +1 more source

Model order reduction of thermo-mechanical models with parametric convective boundary conditions: focus on machine tools. [PDF]

Comput Mech, 2021
Hernández-Becerro P, Spescha D, Wegener K.   +2 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Model-Order Reduction of Multistage Cascaded Models for Digital Predistortion

IEEE Journal of Microwaves
This paper explores the benefits of utilizing multistage cascaded (CC) behavioral models for digital predistortion (DPD) linearization of wideband high-efficiency power amplifiers (PAs).
Raul Criado, Wantao Li, William Thompson, Gabriel Montoro, Kevin Chuang, Pere L. Gilabert   +5 more
doaj   +1 more source

Efficient Analysis of Structures with Rotatable Elements Using Model Order Reduction [PDF]

Radioengineering, 2016
This paper presents a novel full-wave technique which allows for a fast 3D finite element analysis of waveguide structures containing rotatable tuning elements of arbitrary shapes.
G. Fotyga, K. Nyka
doaj  

Model order reduction with applications [PDF]

, 2021
Model order reduction is an integral approach to solving high-dimensional systems of ordinary and partial differential equations. As the needs for processing large amounts of data, resulting in high-order models, are only increasing, this approach will understandably stay relevant. Reduced basis methods are discussed, with the focus being on the proper
openaire  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source