Results 91 to 100 of about 1,373,381 (258)

Model order reduction for bifurcating phenomena in fluid-structure interaction problems. [PDF]

Int J Numer Methods Fluids, 2022
Khamlich M, Pichi F, Rozza G.
europepmc   +1 more source

Interconnection-based model order reduction - a survey

European Journal of Control
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Scarciotti, G, Astolfi, A
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Hybrid Approach for Model Order Reduction of Barotropic Quasi-Geostrophic Turbulence

Fluids, 2018
We put forth a robust reduced-order modeling approach for near real-time prediction of mesoscale flows. In our hybrid-modeling framework, we combine physics-based projection methods with neural network closures to account for truncated modes.
Sk. Mashfiqur Rahman, Omer San, Adil Rasheed   +2 more
doaj   +1 more source

Data-driven kinematics-consistent model order reduction of fluid-structure interaction problems: application to deformable microcapsules in a Stokes flow. [PDF]

J Fluid Mech, 2023
Dupont C, De Vuyst F, Salsac AV.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Model order reduction preconditioning of parameterized Poisson equations

四川大学学报. 自然科学版
This paper aims at the fast numerical solution of parameterized Poisson equation.A preconditioned conjugate gradient （PCG） method based on the model order reduction method is proposed to speed up the solution of the obtained discrete linear system.First，
HU Qixiao, XU Youcai, ZHANG Shiquan
doaj  

Model order reduction of flow based on a modular geometrical approximation of blood vessels. [PDF]

Comput Methods Appl Mech Eng, 2021
Pegolotti L, Pfaller MR, Marsden AL, Deparis S.   +3 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source