Results 71 to 80 of about 4,816,952 (284)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Basic principles and aims of model order reduction in compliant mechanisms [PDF]
Mechanical Sciences, 2011 Model order reduction appears to be beneficial for the synthesis and simulation of compliant mechanisms due to computational costs. Model order reduction is an established method in many technical fields for the approximation of large-scale linear time ...
M. Rösner, R. Lammering
doaj +1 more source
Scalable Symbolic Model Order Reduction [PDF]
2008 IEEE International Behavioral Modeling and Simulation Workshop, 2008 Symbolic model order reduction (SMOR) is to reduce the complexity of a model with symbolic parameters. It is an important problem in analog circuit synthesis and digital circuit modeling with process variations. However, existing symbolic model order reduction (SMOR) methods do not scale well with the number of symbols or with the model order.
Yiyu Shi, Lei He, C.-J. Richard Shi
openaire +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Model order reduction for a flow past a wall-mounted cylinder
Archives of Mechanics, 2016 Reduced order models allow quickly predict fluid behaviour and to better understand flow phenomena. They are the key enablers of closed-loop flow control.
W. Stankiewicz +4 more
doaj +1 more source
Balanced Truncation Model Reduction of a Nonlinear Cable-Mass PDE System with Interior Damping
, 2018 We consider model order reduction of a nonlinear cable-mass system modeled by a 1D wave equation with interior damping and dynamic boundary conditions. The system is driven by a time dependent forcing input to a linear mass-spring system at one boundary.
Batten, Belinda A. +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Order Reduction of the Radiative Heat Transfer Model for the Simulation of Plasma Arcs
, 2015 An approach to derive low-complexity models describing thermal radiation for the sake of simulating the behavior of electric arcs in switchgear systems is presented.
Fagiano, Lorenzo, Gati, Rudolf
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source