Results 51 to 60 of about 1,373,381 (258)

Application of multiphysics model order reduction to doppler/neutronic feedback

EPJ Nuclear Sciences & Technologies, 2019
In this paper, a proper orthogonal decomposition based reduced-order model is presented for parametrized multiphysics computations. Our application physics is Doppler feedback in a simplified model of the molten salt fast reactor concept.
German Peter, Ragusa Jean C., Fiorina Carlo   +2 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Model order reduction

, 2021
This is the first chapter of a three-volume series dedicated to theory and application of Model Order Reduction (MOR). We motivate and introduce the basic concepts and notation, with reference to the two main cultural approaches to MOR: the system-theoretic approach employing state-space models and transfer function concepts (Volume 1), and the ...
Benner, P. ; https://orcid.org/0000-0003-3362-4103, Grivet-Talocia, S., Quarteroni, A., Rozza, G., Schilders, W., Silveira, L.   +5 more
openaire   +2 more sources

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Consensus Standards and Recommendations for Developmental and Cognitive Surveillance, Screening, and Evaluation in Sickle Cell Disease: Executive Summary From the National Alliance of Sickle Cell Centers Neurocognitive Workgroup

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz, Donna Murdaugh, Andrew M. Heitzer, Jennifer N. Longoria, Wendy Santos‐Modesitt, Arianna Martin, Judy Cavazos, Jeff Schatz, Catherine R. Hoyt, Alison King, Eboni I. Lance, Steven Hardy, Marsha Treadwell   +12 more
wiley   +1 more source

A computationally effective time-restricted stability preserving H2-optimal model order reduction approach

Results in Control and Optimization, 2023
Several approaches for reducing model order on the definite time segments have become the topic of investigation in a series of papers that bring challenges during application in a large-scale setting.
Xin Du, Kife I. Bin Iqbal, M. Monir Uddin, Md. Tanzim Hossain, Md. Nazmul Islam Shuzan   +4 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

A technique for non-intrusive greedy piecewise-rational model reduction of frequency response problems over wide frequency bands

Journal of Mathematics in Industry, 2022
In the field of model order reduction for frequency response problems, the minimal rational interpolation (MRI) method has been shown to be quite effective.
Davide Pradovera, Fabio Nobile
doaj   +1 more source

Model order reduction for stochastic nonlinear systems

2017 IEEE 56th Annual Conference on Decision and Control (CDC), 2017
The problem of model reduction for stochastic nonlinear systems is addressed with the moment matching method. We characterize the steady-state of nonlinear stochastic systems exploiting a stochastic version of the center manifold theorem. Exploiting the steady-state response we formulate the notion of moment for stochastic nonlinear systems and we ...
Giordano Scarciotti, Andrew R. Teel
openaire   +2 more sources

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source