Results 141 to 150 of about 1,700,235 (339)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Robust Predictive Functional Control for Quadrotor Flight Systems

Drones
Predictive Functional Control (PFC) has a control structure similar to Model Predictive Control (MPC), determining control inputs by predicting future states using a motion model.
Kai Masuda, Kenji Uchiyama
doaj   +1 more source

Asynchronous Packetized Model Predictive Control

, 2015
This chapter studies an asynchronous packet-based predictive schemer for single-loop control systems. The main goal is reducing the performance degradation caused by data dropouts in networked systems. To this end, the method proposes the use of a model predictive controller and a buffer at the actuator side. Packets are transmitted through the network
Jurado Flores, Isabel, Millán Gata, Pablo   +1 more
openaire   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Towards model predictive control: online predictions of ammonium and nitrate removal by using a stochastic ASM [PDF]

, 2018
Peter Alexander Stentoft, Thomas Munk-Nielsen, Luca Vezzaro, Henrik Madsen, Peter Steen Mikkelsen, Jan Kloppenborg Møller   +5 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Wind turbine control with constraint handling: a model predictive control approach [PDF]

, 2012
Henriksen, Jonkman, Kanev, Kumar, L.C. Henriksen, M.H. Hansen, N.K. Poulsen   +6 more
core   +2 more sources

Performance evaluation of model predictive control method for neutral point clamped inverter

, 2021
Ozan Gülbudak, Mustafa Gökdağ
openalex   +2 more sources

Model-Free Predictive Current Control of Five-Phase PMSM Drives [PDF]

, 2023
Wentao Huang, Yijia Huang, Dezhi Xu
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source