Results 161 to 170 of about 720,153 (314)

A Distributed Approach to Efficient Model Predictive Control of Building HVAC Systems [PDF]

open access: yes, 2012
Model based predictive control (MPC) is increasingly being seen as an attractive approach in controlling building HVAC systems. One advantage of the MPC approach is the ability to integrate weather forecast, occupancy information and utility price ...
Putta, Vamsi   +4 more
core   +1 more source

Model Predictive Control of Underwater Tethered Payload

open access: yesApplied Sciences
A fully automated, buoy-based deployment sensor system is being developed to acquire high-quality water column data, and requires a controller to accurately position an array of sensors at various depths.
Mark O’Connor   +2 more
doaj   +1 more source

Bisimulation metric for Model Predictive Control

open access: yesCoRR
Model-based reinforcement learning has shown promise for improving sample efficiency and decision-making in complex environments. However, existing methods face challenges in training stability, robustness to noise, and computational efficiency. In this paper, we propose Bisimulation Metric for Model Predictive Control (BS-MPC), a novel approach that ...
Yutaka Shimizu, Masayoshi Tomizuka
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Deep Operator Neural Network Model Predictive Control

open access: yesIEEE Open Journal of Control Systems
In this paper, we consider the design of model predictive control (MPC) algorithms based on deep operator neural networks (DeepONets) (Lu et al. 2021).
Thomas O. de Jong   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Novel methods that improve feedback performance of model predictive control with model mismatch [PDF]

open access: yes, 2009
textModel predictive control (MPC) has gained great acceptance in the industry since it was developed and first applied about 25 years ago [1]. It has established its place mainly in the advanced control community.
Thiele, Dirk
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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