Results 91 to 100 of about 1,044,778 (303)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Fractional Model Reference Adaptive PIλDμ Control

Journal of New Results in Science, 2016
This study explains the auto-adjustable fractional order the proportional–integral–derivative (PID) controller design methodology by using the technique of fractional model reference adaptive control (fractional MRAC).
Hüseyin Arpacı, Ömerül Faruk Özgüven, Mehmet Serhat Can   +2 more
doaj  

Auto-Tuning by Using Double Extended Kalman-Bucy Filter: An Application to Dc Motor for Controlling Speed

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2021
In this study, a modified adaptive control algorithm is proposed and investigated. The algorithm consists of a controller, an estimator and an auxiliary model like in model reference adaptive control strategy.
Hakan Kızmaz
doaj  

Adaptive control and noise suppression by a variable-gain gradient algorithm [PDF]

An adaptive control system based on normalized LMS filters is investigated. The finite impulse response of the nonparametric controller is adaptively estimated using a given reference model. Specifically, the following issues are addressed: The stability
Mehta, R. S., Merhav, S. J.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

THE MODEL REFERENCE ADAPTIVE SYSTEM IN THE DYNAMIC INPUT‐OUTPUT MODEL

Papers in Regional Science, 1990
In this paper we explore the use of the Model Reference Adaptive System (MRAS) in a dynamic socio-economic enviroment. We prove the existence of adaptation laws which ensure that the error equation in MRAS for a dynamic input-output model is asymptotically stable. The resulting theorems are appraised through some numerical simulations.
Yuzuru Miyata, Etsuo Yamamura
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Optimal Control Modification Adaptive Law for Time-Scale Separated Systems [PDF]

, 2010
Recently a new optimal control modification has been introduced that can achieve robust adaptation with a large adaptive gain without incurring high-frequency oscillations as with the standard model-reference adaptive control.
Nguyen, Nhan T.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Stable Maximum Descent: An Improved Method of Reference Model Adaptive Control

Measurement + Control, 1974
An improved method of reference model adaptive control is developed which provides fast adaptation of system parameters. Application of the theory is demonstrated on a practical example with three adaptive variables.
J. W. Green, P. H. Walker
doaj   +1 more source