Results 71 to 80 of about 33,998,602 (296)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Obtaining the center of gravity, inertia parameters and finite element approximation models of electromagnetic nonlinearity on 6DOF magnetic levitation system by adaptive control method

open access: yesNihon Kikai Gakkai ronbunshu, 2015
This paper provides an adaptive control method for a magnetic levitation using finite element approximation. Thanks to noncontact and frictionless, magnetic levitation can move smoothly and position precisely an object.
Takashi ANDO
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Adaptive System of Precision Control with a Reference Model

open access: yesIFAC Proceedings Volumes, 2011
Abstract A new adaptation algorithm is proposed for adaptive systems with reference model operating independently from the intensity and spectral composition of the input actions and from the range and the rate of variations of parametric and coordinate disturbances. The problem of this algorithm realizability is considered.
V.Yu. Rutkovsky   +2 more
openaire   +1 more source

Adaptive Fault-Tolerant Control for Flight Systems with Input Saturation and Model Mismatch

open access: yesDiscrete Dynamics in Nature and Society, 2013
A novel scheme for fault-tolerant control is proposed in this paper, in which model reference adaptive control method is incorporated with control allocation to cope with simultaneous actuator failures, input saturation, and model mismatch in the flight ...
Man Wang, Jianying Yang, Nan Li
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The full-order state observer speed-sensorless vector control based on parameters identification for induction motor

open access: yesMeasurement + Control, 2019
During the operation of speed-sensorless control system for induction motor, the stator and rotor resistance varies greatly with the change of temperature and the frequency of the rotor side, which affects the estimation of the stator flux and leads to ...
Bo Fan, Zhumu Fu, Leipo Liu, Jiangtao Fu
doaj   +1 more source

A Model Reference Adaptive PID Control for Electromagnetic Actuated Micro-positioning Stage

open access: yes, 2012
This paper presents a model reference adaptive PID controller for controlling a novel compliant flexuresbased XY micro-positioning stage driven by electromagnetic actuators.
Liu JG(刘金国)   +2 more
core  

Predictor-Based Model Reference Adaptive Control [PDF]

open access: yes, 2009
This paper is devoted to robust, Predictor-based Model Reference Adaptive Control (PMRAC) design. The proposed adaptive system is compared with the now-classical Model Reference Adaptive Control (MRAC) architecture.
Lavretsky, Eugene   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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