Results 101 to 110 of about 7,803,855 (292)

Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. [PDF]

, 2015
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding ...
D:A:D study group, ., ESPRIT study group, ., Fux, CA, INSIGHT study group, ., Johnson, MA, Kirk, O, Law, M, Lundgren, JD, Mocroft, A, Moranne, O, Morlat, P, Neuhaus, J, Reiss, P, Ross, M, Royal Free Hospital Clinic Cohort, ., Ryom, L, SMART study group, ., Smith, C, Wentworth, D   +18 more
core  

Audit Risk Assessment Model

International Journal of Economics and Business Administration, 2019
Purpose: The purpose of this study is the development of an audit risk model based on the decomposition of classical Audit Risk Model (ARM) with the addition of elements to assess the risks associated with various aspects of the task. Design/Methodology/Approach: The classical ARM is the basis of our model.
Arzhenovskiy, S. V., Bakhteev, Andrey Vladimirovich, Sinyavskaya, T. G., Hahonova, N. N.   +3 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Complex Model of Risk Assessment of Industrial Processes Mopori

Communications, 2013
Modern day society wants to create optimal living conditions for its citizens and to ensure constant sustainable development. This objective cannot be achieved without reaching the required level of perceived security in complex.
Katarina Holla, Katarina Kampova, Andrea Peterkova, Andrew Collins   +3 more
doaj   +1 more source

Using the Prediction Model Risk of Bias Assessment Tool (PROBAST) to Evaluate Melanoma Prediction Studies. [PDF]

Cancers (Basel), 2022
Kaiser I, Mathes S, Pfahlberg AB, Uter W, Berking C, Heppt MV, Steeb T, Diehl K, Gefeller O.   +8 more
europepmc   +1 more source

Hotspots: Modelling capacity for vector-borne disease risk analysis in New Zealand: A case study of Ochlerotatus camptorhynchus incursions in New Zealand [PDF]

, 2005
This Hotspots case study of Oc. camptorhynchus in New Zealand forms part of the wider aims and objectives of the Hotspots project. The overall aims of the case study were: 1. To evaluate the performance of the Hotspots model as a risk analysis tool for
de Wet, Neil, Hales, Simon, Slaney, David, Warrick, Richard A., Ye, Wei   +4 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Practice-relevant model validation: distributional parameter risk analysis in financial model risk management. [PDF]

Ann Oper Res, 2022
Cummins M, Gogolin F, Kearney F, Kiely G, Murphy B.   +4 more
europepmc   +1 more source

Visualizing Risk Prediction Models

PLOS ONE, 2015
Risk prediction models can assist clinicians in making decisions. To boost the uptake of these models in clinical practice, it is important that end-users understand how the model works and can efficiently communicate its results. We introduce novel methods for interpretable model visualization.The proposed visualization techniques are applied to two ...
Van Belle, Vanya, Van Calster, Ben
openaire   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source