Results 111 to 120 of about 3,666,543 (317)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Evaluating health risk models [PDF]

open access: yesStatistics in Medicine, 2010
AbstractInterest in targeted disease prevention has stimulated development of models that assign risks to individuals, using their personal covariates. We need to evaluate these models and quantify the gains achieved by expanding a model to include additional covariates.
openaire   +3 more sources

Supply Chain Risk Model Recoginition [PDF]

open access: yes
Currently, the meaning and the concept of supply chain risk are not strongly defined, thus supply chain researchers adduce various ways to manage such risks. The paper provides a consecutive survey of risk management approaches in supply chain management
Kļimovs, Ruslans, Merkurjevs, Jurijs
core  

Fuzzy logic with expert judgment to implement an adaptive risk-based access control model for IoT [PDF]

open access: yes, 2019
The Internet of Things (IoT) is becoming the future of the Internet with a large number of connected devices that are predicted to reach about 50 billion by 2020.
Daniel, Joshua   +6 more
core   +1 more source

Complex Model of Risk Assessment of Industrial Processes Mopori

open access: yesCommunications, 2013
Modern day society wants to create optimal living conditions for its citizens and to ensure constant sustainable development. This objective cannot be achieved without reaching the required level of perceived security in complex.
Katarina Holla   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Risk measure modelling [PDF]

open access: yesInterdisciplinary Management Research, 2007
As a phenomenon, risk represents a latent quantity of money or equivalent values needed as a guarantee. We would like to model in some essential way the approach to potential loss caused by various agents. If the interest focuses on security, it is necessary to determine a limit.
openaire   +1 more source

Multi-objective optimal design for flood risk management with resilience objectives [PDF]

open access: yes, 2018
In flood risk management, the divergent concept of resilience of a flood defense system cannot be fully defined quantitatively by one indicator and multiple indicators need to be considered simultaneously.
Su, Hsin-Ting   +7 more
core   +1 more source

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