Results 91 to 100 of about 3,666,543 (317)

An integrated approach to supply chain risk analysis [PDF]

open access: yes, 2012
Despite the increasing attention that supply chain risk management is receiving by both researchers and practitioners, companies still lack a risk culture.
Grimaldi, Sabrina   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling of "Green" Investments Risks

open access: yesBulletin of the South Ural State University. Series "Mathematical Modelling, Programming and Computer Software", 2018
Summary: The practical lack of methods for quantitative assessment of capital-intensive renewable energy projects taking into account the present uncertainty leads to an increase in the riskiness and reduce the amount of ``green'' investment in the economy. It resolves the urgency of the developing approaches to the renewable energy projects assessment.
Mokhov, V. G.   +2 more
openaire   +2 more sources

A risk model for assessing exposure factors influence oil price fluctuations [PDF]

open access: yes, 2023
The impact of oil price volatility on the global economy is considerable. However, the uncertainty of crude oil prices is affected by many risk factors. Several prior studies have examined the factors that impact oil price fluctuations, but these methods
Alshabandar, R., Jaddoa, A., Hussain, A.
core  

Risk Return Trade-Off in Relaxed Risk Parity Portfolio Optimization [PDF]

open access: yes, 2020
This paper formulates a relaxed risk parity optimization model to control the balance of risk parity violation against the total portfolio performance. Risk parity has been criticized as being overly conservative and it is improved by re-introducing the ...
Kwon, Roy   +3 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Audit Risk Model

open access: yes, 2019
Tujuan dari penelitian ini adalah, untuk mengetahui bagaimana risiko audit ditetapkan, bagaimana tingkat materilitas ditentukan, serta bagaimana pengaruh risiko audit terhadap penentuan tingkat risiko.Risiko audit (Audit Risk)- risiko bawaan, risiko pengendalian, dan risiko deteksi - Mungkin dapat kita sebut bahwa didalam risiko audit itu terdapat ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

On a Multiplicative Multivariate Gamma Distribution with Applications in Insurance

open access: yesRisks, 2018
One way to formulate a multivariate probability distribution with dependent univariate margins distributed gamma is by using the closure under convolutions property.
Vadim Semenikhine   +2 more
doaj   +1 more source

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