Results 51 to 60 of about 7,888,061 (295)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges +12 more
wiley +1 more source
Audit Program on Artificial Intelligence (AI)-driven Credit Risk Models [PDF]
Risk Management MagazineFrom an Internal Audit perspective, the integration of Artificial Intelligence (AI) into credit risk modelling through Machine Learning (ML) algorithms presents significant challenges due to the complexity and multidimensional nature of these models ...
Valeria Anna De Palma +4 more
doaj +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
A Contextual Risk Model for the Ellsberg Paradox
, 2011 The Allais and Ellsberg paradoxes show that the expected utility hypothesis and Savage's Sure-Thing Principle are violated in real life decisions. The popular explanation in terms of 'ambiguity aversion' is not completely accepted.
Aerts, Diederik, Sozzo, Sandro
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
Non-Uniqueness of Best-Of Option Prices Under Basket Calibration
RisksThis paper demonstrates that perfectly calibrating a multi-asset model to observed market prices of all basket call options is insufficient to uniquely determine the price of a best-of call option.
Mohammed Ahnouch +2 more
doaj +1 more source
A proposed best practice model validation framework for banks
South African Journal of Economic and Management Sciences, 2017 Background: With the increasing use of complex quantitative models in applications throughout the financial world, model risk has become a major concern. The credit crisis of 2008–2009 provoked added concern about the use of models in finance.
Pieter J. (Riaan) de Jongh +4 more
doaj +1 more source
A bivariate risk model with mutual deficit coverage [PDF]
, 2015 We consider a bivariate Cramer-Lundberg-type risk reserve process with the special feature that each insurance company agrees to cover the deficit of the other.
Boxma, Onno, Ivanovs, Jevgenijs
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Finite element analysis of cardiovascular stent frames: identifying appropriate mesh discretization
Frontiers in Medical EngineeringEngineers use finite element analysis (FEA) to predict the deformations, strains, stresses, and resistive forces of metallic stent frames under in vivo, in vitro, and manufacturing-induced loading conditions.
Brandon A. Lurie +5 more
doaj +1 more source