Results 61 to 70 of about 7,888,061 (295)

Improving Value-at-Risk prediction under model uncertainty

, 2020
Several well-established benchmark predictors exist for Value-at-Risk (VaR), a major instrument for financial risk management. Hybrid methods combining AR-GARCH filtering with skewed-$t$ residuals and the extreme value theory-based approach are ...
Peng, Shige, Yang, Shuzhen, Yao, Jianfeng   +2 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Results of expert judgments on the faults and risks with Autosub3 and an analysis of its campaign to Pine Island Bay, Antarctica, 2009 [PDF]

, 2009
Probabilistic risk assessment is a methodology that can be systematically applied to estimate the risk associated with the design and operation of complex systems.
Brito, Mario P., Griffiths, Gwyn
core  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

On the Capital Allocation Problem for a New Coherent Risk Measure in Collective Risk Theory

Risks, 2016
In this paper we introduce a new coherent cumulative risk measure on a subclass in the space of càdlàg processes. This new coherent risk measure turns out to be tractable enough within a class of models where the aggregate claims is driven by a ...
Hirbod Assa, Manuel Morales, Hassan Omidi Firouzi   +2 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Model uncertainty: When modeling risk leads to a pretense of knowledge

Zagadnienia Filozoficzne w Nauce
The main purpose of the paper is to develop a concept of model uncertainty as opposed to the existing and well-established concept of model risk. Up to date the broad literature on probability not only developed complete probability systems, but also ...
Mateusz Machaj
doaj   +1 more source

ANALISIS PORTOFOLIO SEBAGAI ALAT UNTUK MENGOPTIMALKAN KEUNTUNGAN INVESTASI SAHAM PADA PERUSAHAAN TEKSTIL YANG TERDAFTAR DI BURSA EFEK INDONESIA (BEI) BERDASARKAN MODEL INDEKS TUNGGAL [PDF]

, 2010
This research represent case study at Effect Exchange Indonesia (BEI) with title “Analyze Portofolio As a Means Of To Be Is Optimal Advantage Of Investment Share at Company Of Textile Which Enlist in Effect Exchange Indonesia (BEI) Pursuant To Single ...
Wirawan, Adi
core  

Robust Optimal Risk Sharing and Risk Premia in Expanding Pools

, 2016
We consider the problem of optimal risk sharing in a pool of cooperative agents. We analyze the asymptotic behavior of the certainty equivalents and risk premia associated with the Pareto optimal risk sharing contract as the pool expands.
Knispel, Thomas, Laeven, Roger J. A., Svindland, Gregor   +2 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source