Results 111 to 120 of about 7,641,165 (285)

Statistical Ensemble Theory of Gompertz Growth Model

open access: yesEntropy, 2009
An ensemble formulation for the Gompertz growth function within the framework of statistical mechanics is presented, where the two growth parameters are assumed to be statistically distributed.
Takuya Yamano
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multilevel Ventilation: Theory and Simplified Mathematical Model

open access: yesОбщая реаниматология, 2008
Considering the issues of artificial ventilation (AV) in non-homogenous pathological lung processes (acute lung injury, acute respiratory distress syndrome, pneumonia, etc.), the authors created a mathematical model of multicompartment non-homogenous ...
P. Torok, M. Majek
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Supersymmetric SYK model and random matrix theory

open access: yesJournal of High Energy Physics, 2017
In this paper, we investigate the effect of supersymmetry on the symmetry classification of random matrix theory ensembles. We mainly consider the random matrix behaviors in the N = 1 $$ \mathcal{N}=1 $$ supersymmetric generalization of Sachdev-Ye-Kitaev
Tianlin Li   +3 more
doaj   +1 more source

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