Results 81 to 90 of about 1,025,955 (262)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Model theory of modules

open access: yesAnnals of Pure and Applied Logic, 1984
This paper was a break-through, both in methods and in results. Exemplifying the strong correlation between model theory and algebra in the context of modules, it had great impetus on further developments of not only model theoretic, but also purely algebraic nature, as well as on those where both aspects overlap essentially (cf. e.g.
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Central types of convex fragments of the perfect Jonsson theory

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
In this paper, the central types of convex fragments of the perfect Jonsson theory are considered. The main goal of this paper is to redefine the A.D.
A.R. Yeshkeyev, M.T. Omarova
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Computer-animated model of accommodation and theory of reciprocal zonular action

open access: yesClinical Ophthalmology, 2011
Daniel B Goldberg1,2 1Ophthalmology Department, Drexel College of Medicine, Philadelphia, PA, 2Eye Physicians, Little Silver, NJ, USA Abstract: This report presents a computer-animated model of the structures of accommodation based on new understanding ...
Goldberg DB
doaj  

Contextual measurement model and quantum theory

open access: yesRoyal Society Open Science
We develop a contextual measurement model (CMM) that is used for the clarification of the quantum foundations. This model matches Bohr’s views on the role of experimental contexts.
Andrei Khrennikov
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Theory of planned behavior and smoking: meta-analysis and SEM model

open access: yesSubstance Abuse and Rehabilitation, 2010
Gabriela Topa, Juan Antonio MorianoDepartment of Social and Organizational Psychology, UNED, Madrid, SpainAbstract: To examine if the theory of planned behavior (TPB) predicts smoking behavior, 35 data sets (N = 267,977) have been synthesized, containing
Gabriela Topa, Juan Antonio Moriano
doaj  

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