Results 91 to 100 of about 1,058,068 (314)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Design Model Data Exchange Between Concurrent Engineering Facilities by Means of Model Transformation [PDF]
, 2011 The German Aerospace Center (DLR) is developing the software Virtual Satellite for use in their Concurrent Engineering Facility. Throughout the design process of a spacecraft the software supports engineers to store and manage the data and results of ...
Schaus, Volker +2 more
core
Interplay of Martensitic Phase Transformation and Plastic Slip in Polycrystals [PDF]
, 2013 Inspired by key experimental and analytical results regarding Shape Memory Alloys (SMAs), we propose a modelling framework to explore the interplay between martensitic phase transformations and plastic slip in polycrystalline materials, with an eye ...
Richards, A. W. +3 more
core +1 more source
EnergiesIn order to fully utilize the control degrees of freedom of a multi-three-phase-star smooth-pole permanent magnet synchronous motor (PMSM), this paper first develops a modeling approach using a new matrix transformation method.
Shu Mo +4 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Using schema transformation pathways for data lineage tracing [PDF]
, 2005 With the increasing amount and diversity of information available on the Internet, there has been a huge growth in information systems that need to integrate data from distributed, heterogeneous data sources. Tracing the lineage of the integrated data is
Fan, Hao +4 more
core +1 more source
Applied Computer Systems, 2014 The software system needs to be analyzed and designed before the program code is written. A Computation Independent Model (CIM) and a Platform Independent Model/ Platform Specific Model (PIM/PSM) from Model-Driven Architecture (MDA) will be partially ...
Ovchinnikova Viktoria +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A Thermodynamic Constitutive Model for Stress Induced Phase Transformation in Shape Memory Alloys [PDF]
, 2002 In this paper a thermodynamic constitutive model is developed for stress induced phase transformation in single crystalline and polycrystalline shape memory alloys (SMAs). Volume fractions of different martensite variants are chosen as internal variables
Huang, WM (reprint author), Nanyang Technol Univ, Ctr Adv Numer Engn Simulat, Nanyang Ave, Singapore 639798, Singapore. +5 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source