Results 71 to 80 of about 15,092,034 (255)

Quantifying Correlation Uncertainty Risk in Credit Derivatives Pricing

open access: yesInternational Journal of Financial Studies, 2018
We propose a simple but practical methodology for the quantification of correlation risk in the context of credit derivatives pricing and credit valuation adjustment (CVA), where the correlation between rates and credit is often uncertain or unmodelled ...
Colin Turfus
doaj   +1 more source

Model Uncertainty and Policy Evaluation: Some Theory and Empirics [PDF]

open access: yes
This paper explores ways to integrate model uncertainty into policy evaluation. We first describe a general framework for the incorporation of model uncertainty into standard econometric calculations.
Steven N. Durlauf   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Optimal Policy Under Model Uncertainty: A Structural-Bayesian Estimation Approach [PDF]

open access: yes
In this paper we propose a novel methodology to analyze optimal policies under model uncertainty in micro-founded macroeconomic models. As an application we assess the relevant sources of uncertainty for the optimal conduct of monetary policy within ...
Alexander Kriwoluzky   +1 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Uncertainty and social support as predictors of coping in women experiencing fibromyalgia : a structural model

open access: yes, 2006
This study examined the applicability of Mishel's model of uncertainty in illness (1990) to the adaptation process of women diagnosed with fibromyalgia. The power of uncertainty and social support to predict an uncertainty appraisal and its corresponding
Bowers, Rhonda J.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

ADOB: A Field-Friendly Control Framework for Reliable Robotic Systems via Complementary Integration of Robust and Adaptive Control

open access: yesSensors
Practical robotic systems require control methods that remain reliable under limited computational resources, uncertain environments, and frequent changes in operating conditions.
Jangyeon Park, Kwanho Yu, Jungsu Choi
doaj   +1 more source

Comparing Kalman Filters and Observers for Power System Dynamic State Estimation With Model Uncertainty and Malicious Cyber Attacks

open access: yesIEEE Access, 2018
Kalman filters (KFs) and dynamic observers are two main classes of the dynamic state estimation (DSE) routines. The Power system DSE has been implemented by various KFs, such as the extended KF (EKF) and the unscented KF (UKF).
Junjian Qi, Ahmad F. Taha, Jianhui Wang
doaj   +1 more source

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