Results 71 to 80 of about 766,215 (314)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Measuring the Uncertainty of Predictions in Deep Neural Networks with Variational Inference

open access: yesSensors, 2020
We present a novel approach for training deep neural networks in a Bayesian way. Compared to other Bayesian deep learning formulations, our approach allows for quantifying the uncertainty in model parameters while only adding very few additional ...
Jan Steinbrener   +2 more
doaj   +1 more source

The Impact of a Regional Nuclear Conflict between India and Pakistan: Two Views

open access: yesJournal for Peace and Nuclear Disarmament, 2021
The severity of climatic effects of a regional nuclear conflict between India and Pakistan, involving the use of a hundred Hiroshima-scale nuclear weapons, is contested between two groups; Mills et al.
G. D. Hess
doaj   +1 more source

Comparison of Deterministic and Probabilistic Variational Data Assimilation Methods Using Snow and Streamflow Data Coupled in HBV Model for Upper Euphrates Basin

open access: yesGeosciences, 2023
The operation of upstream reservoirs in mountainous regions fed by snowmelt is highly challenging. This is partly due to scarce information given harsh topographic conditions and a lack of monitoring stations. In this sense, snow observations from remote
Gökçen Uysal   +3 more
doaj   +1 more source

Generalized entropy and model uncertainty [PDF]

open access: yesJournal of Economic Theory, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Improving Re-Identification by Estimating and Utilizing Diverse Uncertainty Types for Embeddings

open access: yesAlgorithms
In most re-identification approaches, embedding vectors are compared to identify the best match for a given query. However, this comparison does not take into account whether the encoded information in the embedding vectors was extracted reliably from ...
Markus Eisenbach   +3 more
doaj   +1 more source

Bayesian Model Averaging and Prior Sensitivity in Stochastic Frontier Analysis

open access: yesEconometrics, 2020
This paper discusses Bayesian model averaging (BMA) in Stochastic Frontier Analysis and investigates inference sensitivity to prior assumptions made about the scale parameter of (in)efficiency. We turn our attention to the “standard” prior specifications
Kamil Makieła, Błażej Mazur
doaj   +1 more source

Probabilistic Models for the Shear Strength of RC Deep Beams

open access: yesApplied Sciences, 2023
A new shear strength determination of reinforced concrete (RC) deep beams was proposed by using a statistical approach. The Bayesian–MCMC (Markov Chain Monte Carlo) method was introduced to establish a new shear prediction model and to improve seven ...
Zhenjun Li   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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