Results 81 to 90 of about 12,063,985 (329)
Application of Heuristic Methods for Polymer Synthesis Process Optimization
Journal of EngineeringA numerical algorithm has been developed for solving the problem of finding optimal conditions for the synthesis of polymers using heuristic optimization methods, and its effectiveness has been evaluated in the investigation of the copolymerization ...
Eldar Miftakhov +2 more
doaj +1 more source
Information and Analytical Web Mapping System “Map of Health Care of Krasnoyarsk Region”
MATEC Web of Conferences, 2016 Approaches to the modern geoinformation web-systems development and technological features of software implementation are considered, their development trends are discussed.
Kadochnikov Alexey +2 more
doaj +1 more source
Extended MHD modeling of the steady solar corona and the solar wind
Living Reviews in Solar Physics, 2018 The history and present state of large-scale magnetohydrodynamic modeling of the solar corona and the solar wind with steady or quasi-steady coronal physics is reviewed.
Tamas I. Gombosi +3 more
doaj +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
A Mathematical Model of Suspension Filtration With Formation of a Consolidated Sediment
Journal of Applied MathematicsA model for suspension filtration in a porous medium is developed with the formation of a consolidating sediment. A system of equations including the equation for determining the pressure and the equations for determining the saturation of the medium by ...
Bakhtiyor Kh. Khuzhayorov +4 more
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source