Results 81 to 90 of about 4,399,350 (329)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Proceedings, MSVSCC 2019 [PDF]

, 2019
Old Dominion University Department of Modeling, Simulation & Visualization Engineering (MSVE) and the Virginia Modeling, Analysis and Simulation Center (VMASC) held the 13th annual Modeling, Simulation & Visualization (MSV) Student Capstone Conference on
Old Dominion University, Department of Modeling, Simulation & Visualization Engineering, Old Dominion University, Virginia Modeling, Analysis and Simulation Center   +1 more
core   +1 more source

Modeling and Simulation of Fuzzy Logic based Maximum Power Point Tracking (MPPT) for PV Application

International Journal of Electrical and Computer Engineering (IJECE), 2018
This paper presents modeling and simulation of maximum power point tracking (MPPT) used in solar PV power systems. The Fuzzy logic algorithm is used to minimize the error between the actual power and the estimated maximum power.  The simulation model was
A. S. Samosir, H. Gusmedi, S. Purwiyanti, E. Komalasari   +3 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Dynamics of quantum information resources in two-flavor neutrino oscillations

European Physical Journal C: Particles and Fields
The burgeoning intersection of particle physics and quantum information science unveils significant connections, particularly in the context of neutrinos–fundamental particles that challenge our understanding of mass, mixing, and coherence at the quantum
K. El Bouzaidi, A. Slaoui, L. B. Drissi, E. H. Saidi, R. Ahl Laamara   +4 more
doaj   +1 more source

Applying the Levels of Conceptual Interoperability Model in Support of Integratability, Interoperability, and Composability for System-of-Systems Engineering [PDF]

Journal of Systemics, Cybernetics and Informatics, 2007
The Levels of Conceptual Interoperability Model (LCIM) was developed to cope with the different layers of interoperation of modeling and simulation applications.
Andreas Tolk, Saikou Diallo, Charles Turnitsa   +2 more
doaj  

Overview on agent-based social modelling and the use of formal languages [PDF]

, 2013
Transdisciplinary Models and Applications investigates a variety of programming languages used in validating and verifying models in order to assist in their eventual implementation.
Casanovas Garcia, Josep, Cela Espín, José M., Kaplan Marcusan, Adriana, Montañola Sales, Cristina, Rubio Campillo, Xavier   +4 more
core   +2 more sources

Multiscale Modeling and Simulation of Nano‐Carriers Delivery through Biological Barriers—A Review

Advanced Theory and Simulations, 2018
The past several decades have witnessed the explosion of nanomedicine for cancer therapy, where notable research efforts have been made in synthesizing and delivering nano‐carriers (NCs) to specific tumor sites.
Xinghua Shi, Falin Tian
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A multistate platform model for time‐to‐event endpoints in oncology clinical trials

CPT: Pharmacometrics & Systems Pharmacology
A multistate platform model was developed to describe time‐to‐event (TTE) endpoints in an oncology trial through the following states: initial, tumor response (TR), progressive disease (PD), overall survival (OS) event (death), censor to the last ...
Chih‐Wei Lin, Mario Nagase, Sameer Doshi, Sandeep Dutta   +3 more
doaj   +1 more source