Results 91 to 100 of about 27,529,067 (324)

Reference-Aware Language Models [PDF]

Proceedings of the 2017 Conference on Empirical Methods in Natural Language Processing, 2017
We propose a general class of language models that treat reference as an explicit stochastic latent variable. This architecture allows models to create mentions of entities and their attributes by accessing external databases (required by, e.g., dialogue generation and recipe generation) and internal state (required by, e.g.
Yang, Z, Blunsom, P, Dyer, C, Ling, W
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Application of Visual Modeling Technique to the Sudan Investment GIS Model

Journal of King Saud University: Engineering Sciences, 2008
In this paper, visual modeling technique was introduced to generate a prototype GIS model for investment projects in Sudan. The modeling approach is implemented using the Unified Modeling Language (UML) as notation and the Unified Process (UP) of object ...
M.A. Gorani, M. A. Kheir Shanan
doaj   +1 more source

Towards a Theory Grounded Theory of Language [PDF]

, 2002
In this paper, we build upon the idea of theory grounding and propose one specific form of theory grounding, a theory of language. Theory grounding is the idea that we can imbue our embodied artificially intelligent systems with theories by modeling the ...
Kosolapov, Oleksandr V., Lykken, Troy R., Mislivec, Eric J., Prince, Christopher G.   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Dual Rectified Linear Units (DReLUs): A Replacement for Tanh Activation Functions in Quasi-Recurrent Neural Networks

, 2017
In this paper, we introduce a novel type of Rectified Linear Unit (ReLU), called a Dual Rectified Linear Unit (DReLU). A DReLU, which comes with an unbounded positive and negative image, can be used as a drop-in replacement for a tanh activation function
Dambre, Joni, De Neve, Wesley, Degrave, Jonas, Godin, Fréderic   +3 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Recent advances in deep learning and language models for studying the microbiome

Frontiers in Genetics
Recent advancements in deep learning, particularly large language models (LLMs), made a significant impact on how researchers study microbiome and metagenomics data. Microbial protein and genomic sequences, like natural languages, form a language of life,
Binghao Yan, Yunbi Nam, Lingyao Li, Rebecca A. Deek, Hongzhe Li, Siyuan Ma   +5 more
doaj   +1 more source

Quantifying Uncertainties in Natural Language Processing Tasks

, 2018
Reliable uncertainty quantification is a first step towards building explainable, transparent, and accountable artificial intelligent systems. Recent progress in Bayesian deep learning has made such quantification realizable.
Wang, William Yang, Xiao, Yijun
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source