Results 61 to 70 of about 603,423 (297)

A surrogate modeling and adaptive sampling toolbox for computer based design [PDF]

, 2010
An exceedingly large number of scientific and engineering fields are confronted with the need for computer simulations to study complex, real world phenomena or solve challenging design problems.
Couckuyt, Ivo, Crombecq, Karel, Demeester, Piet, Dhaene, Tom, Gorissen, Dirk   +4 more
core  

A new data assimilation procedure to develop a debris flow run-out model [PDF]

, 2015
Parameter calibration is one of the most problematic phases of numerical modeling since the choice of parameters affects the model\u2019s reliability as far as the physical problems being studied are concerned. In some cases, laboratory tests or physical
Bossi, G., Brezzi, Lorenzo, Cola, Simonetta, Gabrieli, Fabio, Marcato, G., Pastor, M.   +5 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Systematic review of multiscale thermal prediction models for FDM/FFF additive manufacturing: Toward digital twin integration with physics-informed machine learning

Results in Engineering
Fused filament fabrication/fused deposition modeling (FFF/FDM) is a widely used additive manufacturing (AM) technique valued for its affordability, safety, and greater accessibility compared to metal-based AM processes.
Dame Alemayehu Efa, Dejene Alemayehu Ifa
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Matching of an observed event and its virtual model in relation to smart theories, coupled models and supervision of complex procedures—A review

Comptes Rendus. Physique
This contribution aims to illustrate the nature of the observation–modeling (or real–virtual) link, the importance of the exact model (or coupled model) in the matching involved in this link and the use of this link in the supervision of complex ...
Razek, Adel
doaj   +1 more source

Pedestrian simulation: Theoretical models vs. data driven techniques

International Journal of Transportation Science and Technology, 2018
This paper presents a comparison and relative assessment of data driven techniques and conventional theoretical pedestrian simulation models. Data driven methods are applied for simulating phenomena without a priori knowledge of parameter connections ...
George Kouskoulis, Ioanna Spyropoulou, Constantinos Antoniou   +2 more
doaj   +1 more source

Old Game, New Rules: Rethinking The Form of Physics

, 2016
We investigate the modeling capabilities of sets of coupled classical harmonic oscillators (CHO) in the form of a modeling game. The application of simple but restrictive rules of the game lead to conditions for an isomorphism between Lie-algebras and ...
Baumgarten, Christian
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Modeling and Simulation in Engineering Design and Technology: Improving Project/Product Performance

International Journal of Technology, 2014
The use of modeling and simulation (M&S) to increase project or product performance within engineering design and technology is well recognized. The reasons for increasing the use of modeling and simulation applications include the ability to simulate ...
Mohammed Ali Berawi
doaj   +1 more source