Results 161 to 170 of about 5,613,073 (287)

Comparison between Communicated and Calculated Exposure Estimates Obtained through Three Modeling Tools. [PDF]

Int J Environ Res Public Health, 2020
Spinazzè A, Borghi F, Magni D, Rovida C, Locatelli M, Cattaneo A, Cavallo DM.   +6 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Sequence modeling tools to decode the biosynthetic diversity of the human microbiome. [PDF]

mSystems
Dason MS, Corà D, Re A.
europepmc   +1 more source

Can Predictive Modeling Tools Identify Patients at High Risk of Prolonged Opioid Use After ACL Reconstruction? [PDF]

Clin Orthop Relat Res, 2020
Anderson AB, Grazal CF, Balazs GC, Potter BK, Dickens JF, Forsberg JA.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A database for evaluating the InMAP, APEEP, and EASIUR reduced complexity air-quality modeling tools. [PDF]

Data Brief, 2020
Baker KR, Amend M, Penn S, Bankert J, Simon H, Chan E, Fann N, Zawacki M, Davidson K, Roman H.   +9 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

An nf-core framework for the systematic comparison of alternative modeling tools: the multiple sequence alignment case study. [PDF]

NAR Genom Bioinform
Santus L, Espinosa-Carrasco J, Rauschning L, Mir-Pedrol J, Trujnara I, Vignoli A, Mansouri L, Baltzis A, Floden EW, Di Tommaso P, Garriga E, Gudyś A, Deorowicz S, Gilchrist C, Steinegger M, Notredame C.   +15 more
europepmc   +1 more source

Towards a widespread adoption of metabolic modeling tools in biopharmaceutical industry: a process systems biology engineering perspective. [PDF]

NPJ Syst Biol Appl, 2020
Richelle A, David B, Demaegd D, Dewerchin M, Kinet R, Morreale A, Portela R, Zune Q, von Stosch M.   +8 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source