Results 181 to 190 of about 28,765,428 (344)

Evaluation of tools for process modeling

open access: yes, 2017
This diploma thesis deals with the modeling and evaluation tools that are used for process modeling. The aim is to provide a method of selecting the most appropriate tool for selected requirements.
Engeová, Andrea
core  

Thermal error modelling of machine tools based on ANFIS with fuzzy c-means clustering using a thermal imaging camera

open access: yes, 2015
Thermal errors are often quoted as being the largest contributor to CNC machine tool errors, but they can be effectively reduced using error compensation.
Longstaff, Andrew P.   +4 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Application of ANN and ANFIS Prediction Models for Thermal Error Compensation on CNC Machine Tools

open access: yes
Thermal errors can have significant effects on Computer Numerical Control (CNC) machine tool accuracy. The errors come from thermal deformations of the machine elements caused by heat sources within the machine structure or from ambient temperature ...
Abdulshahed, Ali
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

DYNAMIC MODEL OF DEEP HOLE DRILLING SPECIAL TOOL FOR HARD MATERIALS LARGE DIAMETER TUBE PLATE TREATING

open access: yesAdvanced Engineering Research, 2012
Features of the mathematical modeling of drilling tools modernized for drilling deep holes are studied. A mathematical model of drilling, questions of stability, and existence of the drilling process are considered.
Tatyana S. Onoyko   +2 more
doaj  

The cognitive science of modeling tools

open access: yesSoftware and Systems Modeling
Abstract Model-driven engineering (MDE) seeks to abstract and automate software development through the systematic use of models and transformations. Despite its conceptual rigor, its tools often impose cognitive burdens that hinder adoption and fluency. This paper explores how modeling tools function as cognitive
Alfonso Pierantonio   +2 more
openaire   +1 more source

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