Results 201 to 210 of about 341,194 (266)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Computational chemistry methods based on MNDO and tools for improving their accuracy. [PDF]

J Mol Model
Stewart JJP.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Digital Medicine and Artificial Intelligence in Chronic Myeloid Leukemia: Current Applications, Challenges, and Future Directions. [PDF]

Cureus
Asadov C, Shirinova A, Alimirzoyeva Z, Hasanova A.   +3 more
europepmc   +1 more source

AI and Robotics Advancement in Analytical Mineral Characterization and Mining Processes: A Review and Research Trends Analysis. [PDF]

Top Curr Chem (Cham)
Mkhohlakali A, Toona MP, Mogashane T, Rampfumedzi T, Madzivha P, Letsoalo MR, Ntsasa N, Sehata J, Mukwevho N, Ncedo T, Mabowa MH, Tshilongo J.   +11 more
europepmc   +1 more source

Restoring the Florida Everglades: Insights on Integrating Sea Level Rise into Decision-Support Tools. [PDF]

Environ Manage
Castellano S, Clarke M, D'Acunto L, Romañach S, Cadaval S.   +4 more
europepmc   +1 more source

Taxonomical modeling and classification in space hardware failure reporting. [PDF]

Sci Rep
Palacios D, Hill TR.
europepmc   +1 more source

ASAS-NANP symposium: mathematical modeling in animal nutrition: training the future generation in data and predictive analytics for sustainable development. A summary of the 2024 symposium.

J Anim Sci
Tedeschi LO, Menendez Iii HM.
europepmc   +1 more source