Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The distribution of the number of academic publications as a function of citation count for a given year is remarkably similar from year to year. We measure this similarity as a width of the distribution and find it to be approximately constant from year
Anthony, H. +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria [PDF]
Fabien Llambi +7 more
openalex +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Investigation of Ti-Pt-V high temperature shape memory alloys towards aerospace applications: A cluster expansion screening [PDF]
TiPt has a higher martensitic transformation above 1200 K, which makes it a good candidate for HTMSAs. However, TiPt exhibits C′ = -32GPa. A new class of Ti-Pt-V systems was predicted using cluster expansion.
Mashamaite Mordecai +2 more
doaj +1 more source
Time-varying parametric modelling and time-dependent spectral characterisation with applications to EEG signals using multi-wavelets [PDF]
A new time-varying autoregressive (TVAR) modelling approach is proposed for nonstationary signal processing and analysis, with application to EEG data modelling and power spectral estimation.
Billings, S.A., Liu, J., Wei, H.L.
core
Monsoon changes for 6000 years ago: Results of 18 simulations from the Paleoclimate Modeling Intercomparison Project (PMIP) [PDF]
Sylvie Joussaume +35 more
openalex +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Akka as a tool for modelling and managing a smart grid system
The article addresses big data processing challenges, fault tolerance, and consumer interaction in a smart grid network management system. It analyses the use of Akka for agent-based modelling of smart grid systems, which enables the creation of ...
Mykola Yaroshynskyi +4 more
doaj +1 more source

