Social Influence in Australian University Institutional Eating: A Qualitative Content Analysis. [PDF]
Pitman KA+3 more
europepmc +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Eltonian Niche Modelling: Applying Joint Hierarchical Niche Models to Ecological Networks. [PDF]
Dehling DM, Lai HR, Stouffer DB.
europepmc +1 more source
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Visual preferences for communicating modelling: a global analysis of COVID-19 policy and decision makers. [PDF]
Hadley L+4 more
europepmc +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Visual modelling can optimise sticky trap design for simultaneous monitoring of multiple species of insect pests. [PDF]
Roberts NS+6 more
europepmc +1 more source
The World Health Organization 2030 goals for Taenia solium : insights and perspectives from transmission dynamics modelling [PDF]
CystiTeam Group for Epidemiology and Modelling of Taenia solium Taeniasis/Cysticercosis, the+3 more
core +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Strategizing towards the future hospital: a systems thinking approach. [PDF]
Kumar A+6 more
europepmc +1 more source