Results 21 to 30 of about 3,680,706 (288)

The roadmap towards elimination of lymphatic filariasis by 2030: insights from quantitative and mathematical modelling [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
The Global Programme to Eliminate Lymphatic Filariasis was launched in 2000 to eliminate lymphatic filariasis (LF) as a public health problem by 1) interrupting transmission through mass drug administration (MDA) and 2) offering basic care to those ...
NTD Modelling Consortium Lymphatic Filariasis Group
doaj   +1 more source

Harnessing peak transmission around symptom onset for non-pharmaceutical intervention and containment of the COVID-19 pandemic

open access: yesNature Communications, 2021
Transmission by pre-symptomatic and asymptomatic viral carriers makes intervention and containment of the COVID-19 extremely challenging. Here, the authors construct an epidemiological model that focuses on transmission around the symptom onset ...
Liang Tian   +11 more
doaj   +1 more source

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goal for schistosomiasis [version 1; peer review: 2 approved, 1 approved with reservations]

open access: yesGates Open Research, 2019
Schistosomiasis remains one of the neglected tropical diseases (NTDs) impacting millions of people around the world. The World Health Organization (WHO) recently proposed a goal of elimination as a public health problem (EPHP) for schistosomiasis to be ...
NTD Modelling Consortium Schistosomiasis Group
doaj   +1 more source

Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper

open access: yesJournal of Translational Medicine, 2023
Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio.
Chao Chen   +4 more
doaj   +1 more source

Modelling ethnogenesis [PDF]

open access: yesBiosystems, 2022
Following the ideas of L.N.Gumilev, we introduce the mathematical model of ethnogenesis which describes the dynamics of subgroups in the developing polity in terms of ordinary differential equations. The bust dynamics associated with the rise and fall of civilisations is modelled as an excitation process, which is the non-linear phenomenon, well known ...
Piunovskiy, Alexey, Vasiev, Bakhtier
openaire   +3 more sources

Insights from mathematical modelling and quantitative analysis on the proposed WHO 2030 targets for visceral leishmaniasis on the Indian subcontinent [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
doaj   +1 more source

Frequent and unpredictable changes in COVID-19 policies and restrictions reduce the accuracy of model forecasts

open access: yesScientific Reports, 2023
Between June and August 2020, an agent-based model was used to project rates of COVID-19 infection incidence and cases diagnosed as positive from 15 September to 31 October 2020 for 72 geographic settings.
Farah Houdroge   +11 more
doaj   +1 more source

Modeling needs user modeling

open access: yesFrontiers in Artificial Intelligence, 2023
Modeling has actively tried to take the human out of the loop, originally for objectivity and recently also for automation. We argue that an unnecessary side effect has been that modeling workflows and machine learning pipelines have become restricted to only well-specified problems.
Mustafa Mert Çelikok   +3 more
openaire   +5 more sources

Protocol for the production of micro- and nanoplastic test materials

open access: yesMicroplastics and Nanoplastics, 2023
Micro- and nanoplastics (MNP) are ubiquitous, but little is known about the risks they pose to human health. Currently available data are of limited use for developing relevant risk assessments due to poor quality control, the lack of a standardised ...
Luke A. Parker   +8 more
doaj   +1 more source

Modelling probabilistic cache representativeness in the presence of arbitrary access patterns [PDF]

open access: yes, 2016
Measurement-Based Probabilistic Timing Analysis (MBPTA) is a promising powerful industry-friendly method to derive worst-case execution time (WCET) estimates as needed for critical real-time embedded systems.
Abella Ferrer, Jaume   +2 more
core   +1 more source

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