Results 31 to 40 of about 3,231,941 (243)
A RBA model for the chemostat modeling [PDF]
Extended version of conference paper to appear in Conference on Decision and Control ...
Dinh, Marc, Fromion, Vincent
openaire +9 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
When searching for nature rules we encounter a fundamental difficulty: for technical reasons we are not able to investigate the whole Nature - we have to explore its sections i.e. empirical systems (structures). However, even then it might happen that the system is too complex and its comprehensive, direct investigation is impossible.
openaire +3 more sources
Nested Models and Model Uncertainty [PDF]
AbstractUncertainty about the appropriate choice among nested models is a concern for optimal policy when policy prescriptions from those models differ. The standard procedure is to specify a prior over the parameter space, ignoring the special status of submodels (e.g., those resulting from zero restrictions).
Kriwoluzky, A., Stoltenberg, C.A.
openaire +8 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Computational and Mathematical Modelling of the EGF Receptor System [PDF]
This chapter gives an overview of computational and mathematical modelling of the EGF receptor system. It begins with a survey of motivations for producing such models, then describes the main approaches that are taken to carrying out such modelling, viz.
A Citri+31 more
core +1 more source
Simulation modelling: Educational development roles for learning technologists [PDF]
Simulation modelling was in the mainstream of CAL development in the 1980s when the late David Squires introduced this author to the Dynamic Modelling System.
Riley, David
core +2 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Is the Voter Model a Model for Voters? [PDF]
The voter model has been studied extensively as a paradigmatic opinion dynamics' model. However, its ability for modeling real opinion dynamics has not been addressed. We introduce a noisy voter model (accounting for social influence) with agents' recurrent mobility (as a proxy for social context), where the spatial and population diversity are taken ...
Fernández-Gracia, Juan+4 more
openaire +4 more sources
Text and spatial data mining [PDF]
Parcellation of the human brain Parcellation of the human brain by combining text mining and spatial data mining within a neuroinformatics database. Text mining: Analysis of scientific abstracts.
Finn ˚arup Nielsen+1 more
core +1 more source