Results 81 to 90 of about 1,154,864 (307)

A Simulation Model Articulation of the REA Ontology [PDF]

open access: yes, 2009
This paper demonstrates how the REA enterprise ontology can be used to construct simulation models for business processes, value chains and collaboration spaces in supply chains.
C.L. Dunn   +11 more
core   +2 more sources

Simulation of econometric models [PDF]

open access: yesProceedings of the 6th conference on Winter simulation, 1973
The purposes of this tutorial are to present some fundamental properties of econometric model structures relevant to effective understanding of simulation procedures, and to describe the use of simulation software for analysis and forecasting.The fundamental concepts of model specification are developed formally to provide a logical foundation for ...
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Simulation of low rigidity part machining applied to thin-walled structures [PDF]

open access: yes, 2010
The aim of this study is to evaluate the modelling of machining vibrations of thin-walled aluminium work- pieces at high productivity rate. The use of numerical simulation is generally aimed at giving optimal cutting conditions for the precision and the ...
Arnaud, Lionel   +4 more
core   +4 more sources

Models, Simulations, and Experiments [PDF]

open access: yes, 2002
I discuss the difference between models, simulations, and experiments from an epistemological and an ontological perspective. I first distinguish between “static” models (like a map) and “dynamic” models endowed with the capacity to generate processes. Only the latter can be used to simulate.
openaire   +2 more sources

Modeling and simulation with INSIGHT [PDF]

open access: yesProceedings of the 18th conference on Winter simulation - WSC '86, 1986
The INSIGHT simulation language describes systems in a quick, simple, and compact fashion using a network representation. This description can be entered and simulated using novel interactive facilities that relieve the user of needing to know specific syntax, while promoting a greater understanding of model behavior.
openaire   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

Simulation-based fitness landscape analysis and optimisation of complex problems

open access: yesTechnological and Economic Development of Economy, 2015
Widespread hard optimisation problems in economics and logistics are characterised by large dimensions, uncertainty and nonlinearity and require more powerful methods of stochastic optimisation that traditional ones. Simulation optimisation is a powerful
Galina Merkuryeva, Vitaly Bolshakov
doaj   +1 more source

Modelling and simulation framework for reactive transport of organic contaminants in bed-sediments using a pure java object - oriented paradigm [PDF]

open access: yes, 2006
Numerical modelling and simulation of organic contaminant reactive transport in the environment is being increasingly relied upon for a wide range of tasks associated with risk-based decision-making, such as prediction of contaminant profiles ...
Allan, I.   +3 more
core  

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

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