Results 71 to 80 of about 110,051 (268)
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Simulation of extreme temperature over Odisha during May 2015
Weather and Climate Extremes, 2017 An extreme temperature event (heat wave) over the state of Odisha was unique as it lasted for about 2 weeks in the 3rd and 4th weeks of May 2015. There was a similar severe heat wave in western and central Odisha in the month of April 1998.
K.C. Gouda +3 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
New predictive methodology for severity assessment of corrosion and gouge defects in pipelines
Journal of Engineering and Applied ScienceA major challenge in pipeline integrity is the absence of a standard method to directly compare corrosion severity with mechanical damage like gouges. This work fills that gap with a new machine learning-based approach.
Yassine El Kiri +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Technological and Economic Development of Economy, 2008 This paper investigates problems related to supply chain risk identification and simulation‐ based risk evaluation. Accordingly, the paper is divided into two logical parts.
Ruslan Klimov, Yuri Merkuryev
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
SUN: Stochastic UNsupervised Learning for Data Noise and Uncertainty Reduction
Applied SciencesUnsupervised learning methods significantly benefit various practical applications by effectively identifying intrinsic patterns within unlabelled data.
Nicholas Christakis, Dimitris Drikakis
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source