Results 71 to 80 of about 1,154,864 (307)

Contrail Modeling and Simulation [PDF]

open access: yesAnnual Review of Fluid Mechanics, 2016
There is large uncertainty in the radiative forcing induced by aircraft contrails, particularly after they transform to cirrus. It has recently become possible to simulate contrail evolution for long periods after their formation. We review the main physical processes and simulation efforts in the four phases of contrail evolution, namely the jet ...
Roberto Paoli, Karim Shariff
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Modelling an End to End Supply Chain system Using Simulation [PDF]

open access: yes, 2014
Within the current uncertain environment industries are predominantly faced with various challenges resulting in greater need for skilled management and adequate technique as well as tools to manage Supply Chains (SC) efficiently.
Chilmon, Barbara, Tipi, Nicoleta S.
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Convolutional Neural Network-Based Digital Diagnostic Tool for the Identification of Psychosomatic Illnesses

open access: yesAlgorithms
This paper appraises convolutional neural network (CNN) models’ capabilities in emotion detection from facial expressions, seeking to aid the diagnosis of psychosomatic illnesses, typically made in clinical setups.
Marta Narigina   +2 more
doaj   +1 more source

From Large to Small Scales: Global Models of the ISM

open access: yes, 2003
We review large scale modelling of the ISM with emphasis on the importance to include the disk-halo-disk duty cycle and to use a dynamical refinement of the grid (in regions where steep variations of density and pressure occur) for a realistic modelling ...
A Rosen, FD Kahn, MA Avillez, MA Avillez
core   +3 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

The Repast Simulation/Modelling System for Geospatial Simulation [PDF]

open access: yes, 2007
The use of simulation/modelling systems can simplify the implementation of agent-based models. Repast is one of the few simulation/modelling software systems that supports the integration of geospatial data especially that of vector-based geometries ...
Crooks, AT
core  

Steering in computational science: mesoscale modelling and simulation

open access: yes, 2003
This paper outlines the benefits of computational steering for high performance computing applications. Lattice-Boltzmann mesoscale fluid simulations of binary and ternary amphiphilic fluids in two and three dimensions are used to illustrate the ...
AR Porter   +22 more
core   +1 more source

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