Results 91 to 100 of about 4,097 (260)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics

Frontiers in Bioengineering and Biotechnology
Human tissue simulating materials are currently used in scientific research mainly because they help to avoid possible ethical issues, unlike what happens with studies involving live animals and/or human cadavers.
Lucas Meciano Pereira dos Santos, Marcelo Rodrigues da Cunha, Carlos Henrique Bertoni Reis, Daniela Vieira Buchaim, Daniela Vieira Buchaim, Ana Paula Bernardes da Rosa, Leandro Moreira Tempest, José Augusto Parola da Cruz, Rogério Leone Buchaim, Rogério Leone Buchaim, João Paulo Mardegan Issa, João Paulo Mardegan Issa   +11 more
doaj   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Haptic Rendering of Volumetric Anatomic Models at Sub-voxel Resolution

, 2001
In this paper, a new approach for haptic rendering of high resolution voxel-based anatomic models is presented. For visualization the surface location is determined by a ray-casting algorithm at sub-voxel resolution.
Bernhard Pflesser, Karl Heinz Höhne, Andreas Petersik Bernhard, Andreas Petersik, Ulf Tiede   +4 more
core  

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Design and implementation of modular laparoscopic general surgery models for surgical education

Journal of Minimally Invasive Surgery
Appendectomy, cholecystectomy, and inguinal herniorrhaphy are fundamental procedures in general surgery. These surgeries help trainees develop essential surgical skills, including technical proficiency and surgical planning.
Sung Hyun Kim, Sang Sik Cho, In Geol Ho, Ho Seung Kim, Chang Moo Kang   +4 more
doaj   +1 more source

Rib fractures in the elderly: physiology trumps anatomy

Trauma Surgery & Acute Care Open, 2019
Introduction Rib fractures in elderly patients are associated with increased morbidity and mortality. Predicting which patients are at risk for complications is an area of debate.
Nathan Schmoekel, Jon Berguson, Jerry Stassinopoulos, Efstathios Karamanos, Joe Patton, Jeffrey L Johnson   +5 more
doaj   +1 more source

Anatomically motivated modeling of cortical laminae

NeuroImage, 2014
Improvements in the spatial resolution of structural and functional MRI are beginning to enable analysis of intracortical structures such as heavily myelinated layers in 3D, a prerequisite for in-vivo parcellation of individual human brains. This parcellation can only be performed precisely if the profiles used in cortical analysis are anatomically ...
Miriam Waehnert, Juliane Dinse, Marcel Weiss, Markus N. Streicher, P. Waehnert, Stefan Geyer, Robert Turner, Pierre-Louis Bazin   +7 more
openaire   +3 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Engineering the Future of Heart Failure Therapeutics: Integrating 3D Printing, Silicone Molding, and Translational Development for Implantable Cardiac Devices

Bioengineering
Three-dimensional (3D) anatomic modeling derived from high-resolution medical imaging, such as computed tomography (CT) and magnetic resonance imaging (MRI), has been increasingly adopted in preclinical testing and device development.
Carleigh Eagle, Aarti Desai, Michael Franklin, Robert Pooley, Elizabeth Johnson, Shawn Robinson, Mark Lopez, Rohan Goswami   +7 more
doaj   +1 more source