Results 21 to 30 of about 9,968,795 (309)

Animal Models of Traumatic Brain Injury

open access: yes, 2016
Animal models of traumatic brain injury (TBI) have been the core of the research on the molecular, cellular, and functional effects of the disease. To be able to simulate the heterogeneous aspects of TBI several models have been designed.
Fredrik Clausen, Clausen, Fredrik,
core   +1 more source

Animal Models of Atherosclerosis [PDF]

open access: yes, 2012
Cardiovascular disease is currently the predominant cause of mortality worldwide and its incidence is expected to increase significantly during the next decades owing to the unhealthy effects of modern lifestyle habits (e.g., obesity and lack of physical exercise). Cardiovascular death is frequently associated with acute myocardial infarction or stroke,
Fuster, Jose J.   +4 more
openaire   +3 more sources

Animal Models of Rheumatoid Arthritis [PDF]

open access: yes, 2013
Autoimmunity is a condition in which the host organizes an immune response against its own antigens. Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology, characterized by the presence of chronic inlammatory iniltrates, the development ...
Meza Zavala, Oscar Gustavo   +13 more
core   +1 more source

Generation of human induced pluripotent stem cells carrying albumin-sfGFP reporter

open access: yesStem Cell Research
Current methodologies for hepatocyte induction from human induced pluripotent stem cells (hiPSCs) have limited efficacy due to lack of a functional hepatocyte reporter.
Jinling Wang   +10 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld   +5 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

Models for character animation

open access: yesSoftware Focus, 2001
AbstractGORDON COLLINS and ADRIAN HILTON present a reviewof methods for the constructionand deformation of charactermodels. They consider both stateof the art research and common practice. In particular they review applications, data capture methods, manual model construction, polygonal, parametricand implicit surface representations, basic geometric ...
Gordon Collins, Adrian Hilton 0001
openaire   +5 more sources

A novel efficient strategy to generate liver sinusoidal endothelial cells from human pluripotent stem cells

open access: yesScientific Reports
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells (ECs) that play an important role in liver development and regeneration. Additionally, it is involved in various pathological processes, including steatosis, inflammation,
Shang-Ping Tian   +7 more
doaj   +1 more source

Neuroprotective effects of hypoactive Akkermansia muciniphila in MPTP-induced mouse models of Parkinson’s disease

open access: yesMicrobiology Spectrum
Parkinson’s disease (PD) has been associated with the microbiota-gut-brain axis, and probiotics have been shown to alleviate PD symptoms via various mechanisms.
Jiahui Xi   +5 more
doaj   +1 more source

Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model

open access: yesStem Cell Research & Therapy, 2021
Background Atherosclerosis (AS) is a complex disease caused in part by dyslipidemia and chronic inflammation. AS is associated with serious cardiovascular disease and remains the leading cause of mortality worldwide.
Yanhong Li   +8 more
doaj   +1 more source

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