Results 21 to 30 of about 3,154,795 (303)

Research Models for Studying Vascular Calcification [PDF]

open access: yes, 2020
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen   +4 more
core   +1 more source

Animal Models in Osteosarcoma [PDF]

open access: yesFrontiers in Oncology, 2014
Osteosarcoma (OS) is the most common non-hematologic primary tumor of bone in children and adults. High-dose cytotoxic chemotherapy and surgical resection have improved prognosis, with long-term survival for non-metastatic disease approaching 70%. However, most OS tumors are high grade and tend to rapidly develop pulmonary metastases.
Guijarro, Maria V.   +2 more
openaire   +3 more sources

The CTRP3-AdipoR2 Axis Regulates the Development of Experimental Autoimmune Encephalomyelitis by Suppressing Th17 Cell Differentiation

open access: yesFrontiers in Immunology, 2021
C1q/TNF-related proteins (CTRP) including CTRP3 are a group of secreted proteins which have a complement C1q-like domain in common, and play versatile roles in lipid metabolism, inflammation, tumor metastasis and bone metabolism.
Masanori A. Murayama   +5 more
doaj   +1 more source

Validating Animal Models [PDF]

open access: yes, 2015
This paper responds to a recent challenge for the validity of extrapolation of neurobiological knowledge from laboratory animals to humans. According to this challenge, experimental neurobiology, and thus neuroscience, is in a state of crisis because the
Atanasova, Nina
core   +6 more sources

Animating Volumetric Models

open access: yesGraphical Models, 2001
Summary: This paper describes a technique to animate three-dimensional sampled volumes. The technique gives the animator the ability to treat volumes as if they were standard polygonal models and to use all of the standard animation/motion capture tools on volumetric data.
Nikhil Gagvani, Deborah Silver
openaire   +1 more source

Animal Models of Atherosclerosis [PDF]

open access: yes, 2012
Cardiovascular disease is currently the predominant cause of mortality worldwide and its incidence is expected to increase significantly during the next decades owing to the unhealthy effects of modern lifestyle habits (e.g., obesity and lack of physical exercise). Cardiovascular death is frequently associated with acute myocardial infarction or stroke,
Fuster, Jose J.   +4 more
openaire   +3 more sources

Tourette syndrome research highlights 2015 [version 1; referees: 3 approved] [PDF]

open access: yes, 2016
We present selected highlights from research that appeared during 2015 on Tourette syndrome and other tic disorders. Topics include phenomenology, comorbidities, developmental course, genetics, animal models, neuroimaging, electrophysiology, pharmacology,
Black, Kevin J, Richards, Cheryl A
core   +3 more sources

Animal models of NASH: getting both pathology and metabolic context right [PDF]

open access: yes, 2015
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core   +1 more source

Animal Model of Dermatophytosis [PDF]

open access: yesJournal of Biomedicine and Biotechnology, 2012
Dermatophytosis is superficial fungal infection caused by dermatophytes that invade the keratinized tissue of humans and animals. Lesions from dermatophytosis exhibit an inflammatory reaction induced to eliminate the invading fungi by using the host’s normal immune function.
Shimamura, Tsuyoshi   +2 more
openaire   +2 more sources

Fisetin may protect early porcine embryos from oxidative stress by down-regulating GRP78 levels [PDF]

open access: yesPeerJ
Fisetin is a natural flavonol with a variety of biological activities, including anti-inflammatory and antitumor activities. However, the effect of fisetin on mammalian oocyte and embryo development is unknown, so in this study, we used porcine oocytes ...
Xiu-Wen Yuan   +9 more
doaj   +2 more sources

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