Results 291 to 300 of about 26,772,730 (350)
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Animal models of human disease: zebrafish swim into view
Nature Reviews Genetics, 2007Graham J Lieschke, Peter Currie
exaly +2 more sources
Drug Safety, 1990
A review of the major categories of animal test procedures used in the toxicological assessment of drugs is presented. Problems that persist include low incidence responses, the need for innovation in toxicological methods and current societal attitudes about drugs and chemicals.
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A review of the major categories of animal test procedures used in the toxicological assessment of drugs is presented. Problems that persist include low incidence responses, the need for innovation in toxicological methods and current societal attitudes about drugs and chemicals.
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Pancreatology, 2006
Research on basic mechanisms that regulate pancreatic organogenesis may help to define molecular pathways involved in the development of pancreatic diseases. In this regard, animal models have become an essential part of advancing our research efforts.
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Research on basic mechanisms that regulate pancreatic organogenesis may help to define molecular pathways involved in the development of pancreatic diseases. In this regard, animal models have become an essential part of advancing our research efforts.
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Ophthalmology Clinics of North America, 2005
Employment of animal models in basic research has significantly advanced the understanding of fundamental processes underlying tumorigenesis in retinoblastoma, including elucidating the complex role of pRb and other related protein products in cell cycle regulation, apoptosis, DNA damage responses, and terminal differentiation. The evolution of therapy
R Max, Conway +4 more
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Employment of animal models in basic research has significantly advanced the understanding of fundamental processes underlying tumorigenesis in retinoblastoma, including elucidating the complex role of pRb and other related protein products in cell cycle regulation, apoptosis, DNA damage responses, and terminal differentiation. The evolution of therapy
R Max, Conway +4 more
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2018
Animal assays represent an important stage between in vitro studies and human clinical applications. These models are crucial for biomedical research and regenerative medicine studies, as these offer precious information for systematically assessing the efficacy and risks of recently created biomaterials, medical devices, drugs, and therapeutic ...
da Silva Morais, Alain +2 more
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Animal assays represent an important stage between in vitro studies and human clinical applications. These models are crucial for biomedical research and regenerative medicine studies, as these offer precious information for systematically assessing the efficacy and risks of recently created biomaterials, medical devices, drugs, and therapeutic ...
da Silva Morais, Alain +2 more
openaire +3 more sources
Physiological and Biochemical Zoology, 2010
There is an increasing need to assess the effects of climate and land-use change on habitat quality, ideally from a mechanistic basis. The symposium "Molecules to Migration: Pressures of Life" at the Fourth International Conference in Africa for Comparative Physiology and Biochemistry, Maasai Mara National Reserve, Kenya, 2008, illustrated how the ...
W P, Porter, S, Ostrowski, J B, Williams
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There is an increasing need to assess the effects of climate and land-use change on habitat quality, ideally from a mechanistic basis. The symposium "Molecules to Migration: Pressures of Life" at the Fourth International Conference in Africa for Comparative Physiology and Biochemistry, Maasai Mara National Reserve, Kenya, 2008, illustrated how the ...
W P, Porter, S, Ostrowski, J B, Williams
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Current Protocols in Immunology, 2000
AbstractIn this unit, protocols for growing Helicobacter organisms on plates or in liquid cultures are presented, followed by protocols for infecting mice with Helicobacter felis and H. pylori and for infecting ferrets with H. mustelae. Also, a procedure is described for adapting an H. pylori isolate to growth in mice.
J G, Nedrud, T G, Blanchard
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AbstractIn this unit, protocols for growing Helicobacter organisms on plates or in liquid cultures are presented, followed by protocols for infecting mice with Helicobacter felis and H. pylori and for infecting ferrets with H. mustelae. Also, a procedure is described for adapting an H. pylori isolate to growth in mice.
J G, Nedrud, T G, Blanchard
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2010
As clinical studies reveal that chemotherapeutic agents may impair several different cognitive domains in humans, the development of preclinical animal models is critical to assess the degree of chemotherapy-induced learning and memory deficits and to understand the underlying neural mechanisms.
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As clinical studies reveal that chemotherapeutic agents may impair several different cognitive domains in humans, the development of preclinical animal models is critical to assess the degree of chemotherapy-induced learning and memory deficits and to understand the underlying neural mechanisms.
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Pharmacological Reviews, 2001
The study of pain in awake animals raises ethical, philosophical, and technical problems. We review the ethical standards for studying pain in animals and emphasize that there are scientific as well as moral reasons for keeping to them.
D. Bars, M. Gozariu, S. Cadden
semanticscholar +1 more source
The study of pain in awake animals raises ethical, philosophical, and technical problems. We review the ethical standards for studying pain in animals and emphasize that there are scientific as well as moral reasons for keeping to them.
D. Bars, M. Gozariu, S. Cadden
semanticscholar +1 more source
2001
Experimental animal models are available for the development of new treatment. Murine animal models have particular advantages for comparative study to evaluate the efficacy and safety of different treatment modalities because many mice can be treated at the same time with easy handling. Among several experimental models, murine renal carcinoma (Renca),
N, Nishisaka +4 more
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Experimental animal models are available for the development of new treatment. Murine animal models have particular advantages for comparative study to evaluate the efficacy and safety of different treatment modalities because many mice can be treated at the same time with easy handling. Among several experimental models, murine renal carcinoma (Renca),
N, Nishisaka +4 more
openaire +2 more sources