Results 81 to 90 of about 3,102,841 (203)

DNA replication fork speed acts as a pacer in cortical neurogenesis

Nature Communications
DNA replication fork speed, which controls the rate of genome duplication, has emerged as a key regulator of cellular plasticity. However, its role in neurogenesis remains unexplored.
Jianhong Wang, Yifan Kong, Xuezhuang Li, Dexi Chen, Kun Xiang, Yulian Tan, Lei Shi   +6 more
doaj   +1 more source

Liver regeneration: unraveling the molecular mechanisms and clinical application

Journal of Translational Medicine
The liver’s exceptional capacity sets it apart from other organs in its response to various acute and chronic injuries, known as “liver regeneration”.
Ning Wang, Meihua Guo, Chu Zhang, Rujiao Jiang, Jianlei Bi, Jie Sun, Bo Liu   +6 more
doaj   +1 more source

GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration

Neural Plasticity, 2019
In neurons, Glycogen Synthase Kinase-3β (GSK-3β) has been shown to regulate various critical processes underlying structural and functional synaptic plasticity.
Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec   +2 more
doaj   +1 more source

Complete Rescue of HTLV-1_p12KO Infectivity by Depletion of Monocytes Together with NK and CD8⁺ T Cells

Pathogens
The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1 enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but seroconversion to either virus is not sustained over time, suggesting a progressive ...
Anna Gutowska, Sarkis Sarkis, Mohammad Arif Rahman, Katherine C. Goldfarbmuren, Ramona Moles, Massimiliano Bissa, Melvin Doster, Robyn Washington-Parks, Katherine McKinnon, Isabela Silva de Castro, Luca Schifanella, Genoveffa Franchini, Cynthia A. Pise-Masison   +12 more
doaj   +1 more source

A comparative study of Zinc (II) ions removal by a locally produced Granular activated carbon [PDF]

, 2013
Physiochemical properties of wastewater effluent from the plants of a brewery in Lagos, Nigeria were analyzed. The adsorption capacity of Granular activated carbon from animal horns when compared with the available commercial Granulated ...
Aluyor, E. O., Oboh, I. O.
core   +1 more source

Chromosome-level genome of Cyprinus rubrofuscus ♀ × Sinocyclocheilus grahami ♂ provides high-quality parental haplotype genomes and insights into hybrid economic traits enhancement

BMC Genomics
Cyprinids, the largest and most economically significant family of teleosts, comprise over 600 polyploid species, whose genomic complexity presents challenges in deciphering the genetic basis of phenotypic diversity.
Yanhui Yin, Yuanwei Zhang, Anli Wu, Wei Dao, Jing Long, Xiaofu Pan, Junxing Yang, Xiaoai Wang   +7 more
doaj   +1 more source

Prevalence and management practices of ophthalmic lesions in laboratory mice

Scientific Reports
The regular inspection of the eye health is an essential part of the veterinary care task in an animal facility in order to achieve robust results during experimentation.
Dana Matzek, Sonja Rumpel, Stefan Kassumeh, Andreas Ohlmann, Thomas H. Brill, Bastian Popper   +5 more
doaj   +1 more source

Expression of HIV from a 1-LTR circular DNA in the absence of integration

Retrovirology
Background Like all retroviruses, two kinds of viral DNA are present in the nucleus of HIV-infected cells: integrated DNA and a pool of unintegrated DNA containing linear and circular forms. For the most part, it has been difficult to examine the role of
Corrado Gurgo, Claudio Fenizia, Katherine McKinnon, Ru-ching Hsia, Genoveffa Franchini   +4 more
doaj   +1 more source

Metabolic Adaptation to Following Temperature Acclimation in Fish on the Yun-Gui Plateau

Biology
Temperature is crucial for fish physiology, as metabolism and related physiological processes are directly influenced by thermal energy. Against the backdrop of global warming, climate-induced variations in water temperature increasingly constrain fish ...
Wei Dao, Jing Long, Yanhui Yin, Anli Wu, Yuanchao Chen, Haitao Gao, Xiaofu Pan, Junxing Yang, Xiaoai Wang, Yuanwei Zhang   +9 more
doaj   +1 more source

Sexual dimorphism in the effects of maternal adipose tissue growth hormone receptor deficiency on offspring metabolic health

Biology of Sex Differences
Background The global incidence of obesity continues to rise, which increases the prevalence of metabolic diseases. We previously demonstrated the beneficial effect of adipose-specific growth hormone receptor (Ghr) knockout (KO) on metabolic parameters ...
Liyuan Ran, Xiaoshuang Wang, Rui Ma, Haoan Wang, Yingjie Wu, Zichao Yu   +5 more
doaj   +1 more source