Results 81 to 90 of about 26,772,730 (350)

miR-146a-5p Plays an Oncogenic Role in NSCLC via Suppression of TRAF6

Frontiers in Cell and Developmental Biology, 2020
Non-small cell lung cancer (NSCLC) is the most deadly cancer in the world due to its often delayed diagnosis. Identification of biomarkers with high sensitivity, specificity, and accessibility for early detection, such as circulating microRNAs, is ...
Xiangdong Liu, Xiangdong Liu, Xiangdong Liu, Bo Liu, Bo Liu, Bo Liu, Ruihua Li, Fei Wang, Fei Wang, Fei Wang, Ning Wang, Ning Wang, Ning Wang, Maihe Zhang, Maihe Zhang, Maihe Zhang, Yang Bai, Yang Bai, Yang Bai, Jin Wu, Jin Wu, Jin Wu, Liping Liu, Liping Liu, Liping Liu, Dongyu Han, Dongyu Han, Dongyu Han, Zhiguang Li, Bin Feng, Guangbiao Zhou, Shujing Wang, Shujing Wang, Li Zeng, Li Zeng, Li Zeng, Jian Miao, Yiqun Yao, Bin Liang, Lin Huang, Lin Huang, Qi Wang, Yingjie Wu, Yingjie Wu, Yingjie Wu, Yingjie Wu, Yingjie Wu   +46 more
doaj   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

Antioxidants, 2020
Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat oxidative stress in heart failure. This study aims to determine the pharmacokinetics of repeated oral dosing of Q10 in Cavalier King Charles Spaniels (CKCS ...
Liselotte B. Christiansen, Malene K. Morsing, Maria Josefine Reimann, Torben Martinussen, Zita Birlie, Anne Marie V. Schou-Pedersen, Jens Lykkesfeldt, Lisbeth H. Olsen   +7 more
doaj   +1 more source

Quality of Reporting and Adherence to ARRIVE Guidelines in Animal Studies for Chagas Disease Preclinical Drug Research: A Systematic Review [PDF]

, 2015
Publication of accurate and detailed descriptions of methods in research articles involving animals is essential for health scientists to accurately interpret published data, evaluate results and replicate findings. Inadequate reporting of key aspects of
García Bournissen, Facundo, Gulin, Julián Ernesto Nicolás, Rocco, Daniela Marisa   +2 more
core   +4 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Animal models of acute lung injury

American Journal of Physiology - Lung cellular and Molecular Physiology, 2008
Acute lung injury in humans is characterized histopathologically by neutrophilic alveolitis, injury of the alveolar epithelium and endothelium, hyaline membrane formation, and microvascular thrombi.
G. Matute-Bello, C. Frevert, T. Martin
semanticscholar   +1 more source

Methyl Paraben Affects Porcine Oocyte Maturation Through Mitochondrial Dysfunction

Biomolecules
Parabens are widely used in various industries, which are including chemical, pharmaceutical, food, cosmetic, and plastic processing industries. Among these, methyl paraben (MP) serves as an antimicrobial preservative in processed foods, pharmaceuticals,
Huimei Huang, Chuman Huang, Yinghua Li, Xingwei Liang, Namhyung Kim, Yongnan Xu   +5 more
doaj   +1 more source

Genetic parameters for milk mineral content and acidity predicted by mid-infrared spectroscopy in Holstein–Friesian cows [PDF]

, 2015
peer-reviewedThis article was first published in animal, Volume 9, Issue 05, May 2015, pp 775-780 © The Animal Consortium 2015The aim of the present study was to estimate genetic parameters for calcium (Ca), phosphorus (P) and titratable acidity (TA) in ...
Berry, Donagh, Cassandro, M., de Marchi, M., McParland, Sinead, Penasa, M., Toffanin, V.   +5 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Animal models of sarcopenia

Aging Cell, 2020
Sarcopenia is the age‐related decline in muscle mass and function without any underlying disease. The exact molecular mechanisms responsible for this pathology remain unknown. The use of model organisms, such as mice, rats, flies, and worms, has advanced
Courtney J Christian, G. Benian
semanticscholar   +1 more source