Results 41 to 50 of about 27,460,944 (326)

Animal models in biological and biomedical research - experimental and ethical concerns.

Anais da Academia Brasileira de Ciências, 2019
Animal models have been used in experimental research to increase human knowledge and contribute to finding solutions to biological and biomedical questions.
M. Andersen, L. M. F. Winter
semanticscholar   +1 more source

Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses

Virology Journal, 2023
Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate receptor domains (CRDs), indicating feasible
Bruno Stein Barbosa Menechino, Rodrigo Bentes Kato, Helena Cristina Ferreira Franz, Pedro Eduardo Almeida da Silva, Marcus Corat, Daniel Ferreira de Lima Neto   +5 more
doaj   +1 more source

DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling

Frontiers in Immunology, 2023
Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism.
Tomonori Kaifu, Takumi Maruhashi, Soo-Hyun Chung, Kenji Shimizu, Akira Nakamura, Yoichiro Iwakura   +5 more
doaj   +1 more source

Fluctuations in models of biological macroevolution

, 2005
Fluctuations in diversity and extinction sizes are discussed and compared for two different, individual-based models of biological coevolution. Both models display power-law distributions for various quantities of evolutionary interest, such as the ...
Rikvold, Per Arne
core   +1 more source

Pattern formation in reaction diffusion models with spatially inhomogeneous diffusion coefficients [PDF]

, 1992
Reaction-diffusion models for biological pattern formation have been studied extensively in a variety of embryonic and ecological contexts. However, despite experimental evidence pointing to the existence of spatial inhomogeneities in various biological ...
Benson, D. L., Maini, P. K., Sherratt, J. A.   +2 more
core   +3 more sources

A Method to Identify and Analyze Biological Programs through Automated Reasoning. [PDF]

, 2016
Predictive biology is elusive because rigorous, data-constrained, mechanistic models of complex biological systems are difficult to derive and validate.
and Stephen Emmott, 5, Austin Smith, 2, Boyan Yordanov, 1, Hillel Kugler, 1, Martello, Graziano, Sara-Jane Dunn, 1   +5 more
core   +1 more source

Tapuy lees attenuate amyloid-β toxicity and dopaminergic neurodegeneration more effectively than Tapuy wine in C. elegans models of Alzheimer’s and Parkinson’s disease

Discover Food
Tapuy is a traditional rice wine from the Philippines. We explored the potential of Tapuy wine and its fermentation by-product, lees, in reducing amyloid-beta toxicity in Alzheimer’s disease (AD) and dopaminergic neurodegeneration in Parkinson’s disease (
Mark Joseph R. Remucal, Junelle Rey C. Bacong, Paul Mark B. Medina   +2 more
doaj   +1 more source

Intermittent supplementation with Akkermansia muciniphila and galactooligosaccharides modulates Alzheimer’s disease progression, gut microbiota, and colon short-chain fatty acid profiles in mice

Frontiers in Aging Neuroscience
BackgroundBidirectional communication and mutual regulation between the gastrointestinal tract and the CNS is facilitated through the gut-brain axis. Recent studies have found reduced diversity of the gut microbiota in Alzheimer’s disease (AD) patients ...
Arnas Kunevičius, Akshay Kumar Vijaya, Alessandro Atzeni, Jonas Mingaila, Ieva Šimoliūnė, Rapolas Jamontas, Emilija Keževičiūtė, Miguel Gueimonde, Rolandas Meškys, Daiva Baltriukienė, Silvia Arboleya, Aurelijus Burokas   +11 more
doaj   +1 more source

Relaxation kinetics of biological dimer adsorption models

, 2001
We discuss the relaxation kinetics of a one-dimensional dimer adsorption model as recently proposed for the binding of biological dimers like kinesin on microtubules.
, , , A Vilfan, Bares P.-A., E Frey, F Schwabl, Hoenger A., Page E. S., Privman V. (ed), Privman V. andm Nielaba P., Schütz G.   +11 more
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source