Results 41 to 50 of about 24,835,738 (277)

Autocatalytic Models for the Origin of Biological Homochirality. [PDF]

open access: yesChemical Reviews, 2019
Autocatalytic models for the emergence of homochirality have been of interest for more than half a century. The sole experimental example of such an amplifying autocatalytic reaction is the Soai reaction.
D. Blackmond
semanticscholar   +1 more source

Of (Biological) Models and Simulations [PDF]

open access: yesMOJ Proteomics & Bioinformatics, 2016
Modeling and simulation are recognized as important aspects of the scientific method for more than 70 years but its adoption in biology has been slow. Debates on its representativeness, usefulness, and whether the effort spent on such endeavors is worthwhile, exist to this day.
openaire   +2 more sources

At the Biological Modeling and Simulation Frontier [PDF]

open access: yesPharmaceutical Research, 2009
We provide a rationale for and describe examples of synthetic modeling and simulation (M&S) of biological systems. We explain how synthetic methods are distinct from familiar inductive methods. Synthetic M&S is a means to better understand the mechanisms that generate normal and disease-related phenomena observed in research, and how compounds of ...
C. Anthony Hunt   +7 more
openaire   +5 more sources

Generic model for biological regulation [PDF]

open access: yesF1000Research, 2022
Abstract Substantial portion of molecules in an organism is involved in regulation of a wide spectrum of biological processes. Several models have been presented for various forms of biological regulation, including gene expression regulation and physiological regulation; however, a generic model is missing.
openaire   +2 more sources

MathSBML: a package for manipulating SBML-based biological models [PDF]

open access: yes, 2004
Summary: MathSBML is a Mathematica package designed for manipulating Systems Biology Markup Language (SBML) models. It converts SBML models into Mathematica data structures and provides a platform for manipulating and evaluating these models.
Doyle, John   +3 more
core   +2 more sources

Duplication Models for Biological Networks [PDF]

open access: yesJournal of Computational Biology, 2003
Are biological networks different from other large complex networks? Both large biological and non-biological networks exhibit power-law graphs (number of nodes with degree k, N(k) ~ k-b) yet the exponents, b, fall into different ranges. This may be because duplication of the information in the genome is a dominant evolutionary force in shaping ...
Linyuan Lu   +3 more
openaire   +4 more sources

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

open access: yesScientific Reports, 2016
The potential of a spheroid tumor model composed of cells in different proliferative and metabolic states for the development of new anticancer strategies has been amply demonstrated.
M. Zanoni   +7 more
semanticscholar   +1 more source

Discriminative topological features reveal biological network mechanisms [PDF]

open access: yesBMC Bioinformatics, 2004
BackgroundRecent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and sociological origin.
Manuel Middendorf   +8 more
semanticscholar   +1 more source

BioDiVinE: A Framework for Parallel Analysis of Biological Models [PDF]

open access: yes, 2009
In this paper a novel tool BioDiVinEfor parallel analysis of biological models is presented. The tool allows analysis of biological models specified in terms of a set of chemical reactions. Chemical reactions are transformed into a system of multi-affine
C. Belta   +29 more
core   +2 more sources

Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses

open access: yesVirology Journal, 2023
Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate receptor domains (CRDs), indicating feasible
Bruno Stein Barbosa Menechino   +5 more
doaj   +1 more source

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