Results 41 to 50 of about 30,009,286 (350)

Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses

Virology Journal, 2023
Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate receptor domains (CRDs), indicating feasible
Bruno Stein Barbosa Menechino, Rodrigo Bentes Kato, Helena Cristina Ferreira Franz, Pedro Eduardo Almeida da Silva, Marcus Corat, Daniel Ferreira de Lima Neto   +5 more
doaj   +1 more source

DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling

Frontiers in Immunology, 2023
Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism.
Tomonori Kaifu, Takumi Maruhashi, Soo-Hyun Chung, Kenji Shimizu, Akira Nakamura, Yoichiro Iwakura   +5 more
doaj   +1 more source

MathSBML: a package for manipulating SBML-based biological models [PDF]

, 2004
Summary: MathSBML is a Mathematica package designed for manipulating Systems Biology Markup Language (SBML) models. It converts SBML models into Mathematica data structures and provides a platform for manipulating and evaluating these models.
Doyle, John, Finney, Andrew, Hucka, Michael, Shapiro, Bruce E.   +3 more
core   +2 more sources

Tapuy lees attenuate amyloid-β toxicity and dopaminergic neurodegeneration more effectively than Tapuy wine in C. elegans models of Alzheimer’s and Parkinson’s disease

Discover Food
Tapuy is a traditional rice wine from the Philippines. We explored the potential of Tapuy wine and its fermentation by-product, lees, in reducing amyloid-beta toxicity in Alzheimer’s disease (AD) and dopaminergic neurodegeneration in Parkinson’s disease (
Mark Joseph R. Remucal, Junelle Rey C. Bacong, Paul Mark B. Medina   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Intermittent supplementation with Akkermansia muciniphila and galactooligosaccharides modulates Alzheimer’s disease progression, gut microbiota, and colon short-chain fatty acid profiles in mice

Frontiers in Aging Neuroscience
BackgroundBidirectional communication and mutual regulation between the gastrointestinal tract and the CNS is facilitated through the gut-brain axis. Recent studies have found reduced diversity of the gut microbiota in Alzheimer’s disease (AD) patients ...
Arnas Kunevičius, Akshay Kumar Vijaya, Alessandro Atzeni, Jonas Mingaila, Ieva Šimoliūnė, Rapolas Jamontas, Emilija Keževičiūtė, Miguel Gueimonde, Rolandas Meškys, Daiva Baltriukienė, Silvia Arboleya, Aurelijus Burokas   +11 more
doaj   +1 more source

Relaxation kinetics of biological dimer adsorption models

, 2001
We discuss the relaxation kinetics of a one-dimensional dimer adsorption model as recently proposed for the binding of biological dimers like kinesin on microtubules.
, , , A Vilfan, Bares P.-A., E Frey, F Schwabl, Hoenger A., Page E. S., Privman V. (ed), Privman V. andm Nielaba P., Schütz G.   +11 more
core   +1 more source

Anhedonia in depression: biological mechanisms and computational models.

Current Opinion in Behavioral Sciences, 2018
Anhedonia is a severe condition that describes a near-complete absence of enjoyment, motivation, and interest. A core feature of depression, clinical manifestations of anhedonia can include deficits in experiencing pleasure, approach-related motivated ...
J. Cooper, A. Arulpragasam, M. Treadway
semanticscholar   +1 more source

Realistic Models of Biological Motion

, 1998
The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule.
Ajdari, Ajdari, Ajdari, Astumian, Astumian, Cooke, Cooke, Doering, Edman, Eisenberg, Faucheux, Faucheux, Finer, Gilbert, Goldman, Harada, Hill, Hirose, Hoenger, Hunt, Huxley, Huxley, Imre Derényi, Katz, Kikkawa, Kron, Kull, Leibler, Lymn, Magnasco, Millonas, Millonas, Pate, Pate, Rayment, Rousselet, Sablin, Sleep, Svoboda, Svoboda, Svoboda, Tamás Vicsek, Vale   +42 more
core   +1 more source

A Mathematical Framework for Agent Based Models of Complex Biological Networks [PDF]

, 2010
Agent-based modeling and simulation is a useful method to study biological phenomena in a wide range of fields, from molecular biology to ecology. Since there is currently no agreed-upon standard way to specify such models it is not always easy to use ...
A. S. Jarrah, A. Veliz-Cuba, Abdul Salam Jarrah, David Murrugarra, F. Castiglione, Franziska Hinkelmann, G. U. Y. Pe’er, I. Shmulevich, M. Gardner, M. Pogson, R. Laubenbacher, R. Lidl, R. Thomas, Reinhard Laubenbacher, S. Eubank, S. Hardy, V. Grimm, Z. Wang   +17 more
core   +1 more source