Results 41 to 50 of about 26,501,681 (348)
Translational Oncology, 2021 Drug repurposing is used as a strategy for finding new drugs for cancer. The process is a faster and a more cost-effective way of providing new indications for drugs that can address emerging drug resistance and numerous side effects of chemotherapeutic ...
Paul Mark Medina +2 more
doaj
Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes
BMC Genomics, 2019 Background Accurate structural annotation of genomes is still a challenge, despite the progress made over the past decade. The prediction of gene structure remains difficult, especially for eukaryotic species, and is often erroneous and incomplete.
Laetitia Guillot +10 more
doaj +1 more source
Medicina, 2020 Background and objectives: Cancer incidence is growing with younger patients diagnosed with this disease every year. Improved cancer diagnostics and treatment lead to better survival of cancer patients.
Živilė Gudlevičienė +5 more
doaj +1 more source
An Optimal Likelihood Free Method for Biological Model Selection [PDF]
arXiv, 2022 Systems biology seeks to create math models of biological systems to reduce inherent biological complexity and provide predictions for applications such as therapeutic development. However, it remains a challenge to determine which math model is correct and how to arrive optimally at the answer.
arxiv
Parameter estimation for Boolean models of biological networks [PDF]
, 2009 Boolean networks have long been used as models of molecular networks and play an increasingly important role in systems biology. This paper describes a software package, Polynome, offered as a web service, that helps users construct Boolean network ...
Abdul S. Jarrah +31 more
core +3 more sources
Inference of analytical thermodynamic models for biological networks [PDF]
, 2013 We present an automated algorithm for inferring analytical models of closed reactive biochemical mixtures, on the basis of standard approaches borrowed from thermodynamics and kinetic theory of gases.
Arcidiacono +23 more
core +1 more source
A model for biological oscillations. [PDF]
Proceedings of the National Academy of Sciences, 1981 A model and computation for oscillatory phenomena observed in some biological processes that utilize ion gradients across a membrane is presented. The model contains two main features: (i) active H+ transport pathways in the membrane and (ii) key enzymes having a pH-dependent activity profile and either translocating H+ from outside or producing H+ as ...
openaire +3 more sources
Boolean Models of Bistable Biological Systems
, 2009 This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick +16 more
core +1 more source
Data in Brief, 2023 Here we report the draft genome sequence of the Latilactobacillus curvatus PN39MY strain. The strain was isolated from Lithuanian traditionally (homemade) fermented cucumber. The genome consisted of 83 contigs with a total size of 1,899,018 bp, an N50 of
Eric Banan-Mwine Daliri +3 more
doaj
Mathematical Models and Biological Meaning: Taking Trees Seriously [PDF]
, 2008 We compare three basic kinds of discrete mathematical models used to portray phylogenetic relationships among species and higher taxa: phylogenetic trees, Hennig trees and Nelson cladograms.
Blackburn, David +2 more
core +3 more sources