Results 61 to 70 of about 24,835,738 (277)

Programmatic modeling for biological systems

open access: yesCurrent Opinion in Systems Biology, 2021
AbstractComputational modeling has become an established technique to encode mathematical representations of cellular processes and gain mechanistic insights that drive testable predictions. These models are often constructed using graphical user interfaces or domain-specific languages, with SBML used for interchange.
Alexander L.R. Lubbock, Carlos F. Lopez
openaire   +4 more sources

Analysis of a Model Biological Switch [PDF]

open access: yesSIAM Journal on Applied Mathematics, 1985
A model mechanism proposed by the second author [On pattern formation mechanisms for lepidopteran wing patterns and mammalian coat markings. Philos. Trans. R. Soc. Lond., B 295, 473-496 (1981)] for generating wing patterns and eyespots on butterflies and moths is based on a morphogen (S) activated biological switch for a gene product (g).
Kath, W. L., Murray, J. D.
openaire   +4 more sources

Intermittent supplementation with Akkermansia muciniphila and galactooligosaccharides modulates Alzheimer’s disease progression, gut microbiota, and colon short-chain fatty acid profiles in mice

open access: yesFrontiers in Aging Neuroscience
BackgroundBidirectional communication and mutual regulation between the gastrointestinal tract and the CNS is facilitated through the gut-brain axis. Recent studies have found reduced diversity of the gut microbiota in Alzheimer’s disease (AD) patients ...
Arnas Kunevičius   +11 more
doaj   +1 more source

Sodium benzoate may reduce appetite in Drosophila melanogaster through serotonin upregulation [PDF]

open access: yesArchives of Biological Sciences
Sodium benzoate is a common artificial preservative in processed food, yet little is known about its long-term health effects. Since sodium benzoate could upregulate serotonin, we hypothesized that it may induce satiety and activate processes underlying ...
Nas John Sylvester B.   +1 more
doaj   +1 more source

Relaxation kinetics of biological dimer adsorption models

open access: yes, 2001
We discuss the relaxation kinetics of a one-dimensional dimer adsorption model as recently proposed for the binding of biological dimers like kinesin on microtubules.
  +11 more
core   +1 more source

Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes

open access: yesBMC Genomics, 2019
Background Accurate structural annotation of genomes is still a challenge, despite the progress made over the past decade. The prediction of gene structure remains difficult, especially for eukaryotic species, and is often erroneous and incomplete.
Laetitia Guillot   +10 more
doaj   +1 more source

Kinetic hierarchy and propagation of chaos in biological swarm models [PDF]

open access: yes, 2011
We consider two models of biological swarm behavior. In these models, pairs of particles interact to adjust their velocities one to each other. In the first process, called 'BDG', they join their average velocity up to some noise.
Aoki   +34 more
core   +3 more sources

Mathematical modeling of biological systems [PDF]

open access: yesBriefings in Bioinformatics, 2012
Mathematical and computational models are increasingly used to help interpret biomedical data produced by high-throughput genomics and proteomics projects. The application of advanced computer models enabling the simulation of complex biological processes generates hypotheses and suggests experiments. Appropriately interfaced with biomedical databases,
MOTTA, Santo, PAPPALARDO, FRANCESCO
openaire   +3 more sources

Slow-Freezing Cryopreservation Ensures High Ovarian Tissue Quality Followed by In Vivo and In Vitro Methods and Is Safe for Fertility Preservation

open access: yesMedicina, 2020
Background and objectives: Cancer incidence is growing with younger patients diagnosed with this disease every year. Improved cancer diagnostics and treatment lead to better survival of cancer patients.
Živilė Gudlevičienė   +5 more
doaj   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

open access: yesPopulation Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

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