Results 61 to 70 of about 26,501,681 (348)

A general and simple method for obtaining R2 from generalized linear mixed‐effects models

open access: yes, 2013
The use of both linear and generalized linear mixed‐effects models (LMMs and GLMMs) has become popular not only in social and medical sciences, but also in biological sciences, especially in the field of ecology and evolution.
Shinichi Nakagawa, H. Schielzeth
semanticscholar   +1 more source

Detailed kinship estimation for detecting bias among breeding families in a reintroduced population of the endangered bagrid catfish Tachysurus ichikawai

open access: yesPopulation Ecology, EarlyView.
In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno   +5 more
wiley   +1 more source

Probabilistic models of biological enzymatic polymerization.

open access: yesPLoS ONE, 2021
In this study, hierarchies of probabilistic models are evaluated for their ability to characterize the untemplated addition of adenine and uracil to the 3' ends of mitochondrial mRNAs of the human pathogen Trypanosoma brucei, and for their generative ...
Marshall Hampton   +3 more
doaj   +1 more source

Piecewise deterministic Markov processes in biological models

open access: yes, 2015
We present a short introduction into the framework of piecewise deterministic Markov processes. We illustrate the abstract mathematical setting with a series of examples related to dispersal of biological systems, cell cycle models, gene expression ...
Rudnicki, Ryszard, Tyran-Kaminska, Marta
core   +1 more source

Biological Transactions for Quantitative Models

open access: yesElectronic Notes in Theoretical Computer Science, 2007
AbstractIn this work an extension of stochastic π-calculus with biological transactions is presented. This permits to model multi-reactant multi-product reactions as atomic actions when quantitative information are given. First, the syntax and the semantics are defined, then some transaction properties are discussed.
F. Ciocchetta, C. Priami
openaire   +3 more sources

Optimal SNP filtering strategies for pedigree reconstruction: A case study with wild red‐spotted masu salmon population

open access: yesPopulation Ecology, EarlyView.
In this article, we tested optimal SNP filtering strategies for accurate parentage assignment and pedigree reconstruction for a wild population of red‐spotted masu salmon, Oncorhynchus masou ishikawae. We found that mid‐point filtering in terms of call rate and minor allele frequency performs well for pedigree reconstruction.
Shohei Noda   +6 more
wiley   +1 more source

Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model

open access: yesNature Communications, 2022
Mutations that enhance the activity of protein kinase C alpha (PKCα) are associated with Alzheimer’s Disease. Here, the authors report that the enhanced activity of one variant, PKCα M489V, is sufficient to rewire the brain phosphoproteome, drive ...
Gema Lordén   +9 more
doaj   +1 more source

Animal models are essential to biological research: issues and perspectives

open access: yesFuture Science OA, 2015
The use of animals for scientific purposes is both a longstanding practice in biological research and medicine, and a frequent matter of debate in our societies.
F. Barré-Sinoussi, X. Montagutelli
semanticscholar   +1 more source

Non-standard discretization of biological models [PDF]

open access: yes, 2015
We consider certain types of discretization schemes for differential equations with quadratic nonlinearities, which were introduced by Kahan, and considered in a broader setting by Mickens.
Hone, Andrew N.W., Towler, Kim
core  

Decoding Sequence Classification Models for Acquiring New Biological Insights [PDF]

open access: yes, 2010
Classifying biological sequences is one of the most important tasks in computational biology. In the last decade, support vector machines (SVMs) in combination with sequence kernels have emerged as a de-facto standard.
Andreas Kothmeier   +4 more
core   +2 more sources

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