Results 111 to 120 of about 1,158,124 (312)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

OPTIMIZATION OF PRETREATMENT CONDITIONS OF CARROTS TO MAXIMIZE JUICE RECOVERY BY RESPONSE SURFACE METHODOLOGY [PDF]

Journal of Engineering Science and Technology, 2006
Carrot juice was expressed in a hydraulic press using a wooden set up. Carrot samples pretreated at different designed combinations, using Central Composite Rotatable Design (CCRD), Response Surface Methodology (RSM), of pH, temperature and time were ...
H. K. SHARMA, J. KAUR, C. SINGH, B. SINGH, A. A. SHITANDI   +4 more
doaj  

Data Quality in Predictive Toxicology: Identification of Chemical Structures and Calculation of Chemical Descriptors

, 2000
Every technique for toxicity prediction and for the detection of structure–activity relationships relies on the accurate estimation and representation of chemical and toxicologic properties.
B Pfahringer, Helma, Christoph, Pfahringer, Bernhard, C Helma, S Kramer, Gottmann, E., Kramer, Stefan, Gottmann, Eva, E Gottmann   +8 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Evaluation of Chemical Equilibrium and Non-Equilibrium Properties for LOX/LH2 Reaction Schemes

Journal of Aerospace Technology and Management, 2015
Nine chemical reaction models for equilibrium schemes and six chemical models for non-equilibrium ones are studied, considering different conditions found in real liquid oxygen/liquid hydrogen rocket engines.
Carlos Henrique Marchi, Luciano Kiyoshi Araki   +1 more
doaj  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

A SOLUBILIDADE DOS COMPOSTOS IÔNICOS: COMO OS LICENCIANDOS EM QUÍMICA EXPLICAM O COMPORTAMENTO DO CLORETO DE PRATA?

Ensaio Pesquisa em Educação em Ciências
O trabalho objetivou analisar se licenciandos em Química fazem uso de um modelo teórico de ligação química para explicar a solubilidade de um composto químico. A investigação foi realizada ao longo de três anos, com 55 estudantes do curso de licenciatura
Analice de Almeida Lima, Isauro Beltrán Núnez   +1 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Modeling Chemical Kinetics Graphically

The Chemical Educator, 2012
In literature on chemistry education it has often been suggested that students, at high school level and beyond, can benefit in their studies of chemical kinetics from computer supported activities. Use of system dynamics modeling software is one of the suggested quantitative approaches that could help students develop knowledge about chemical kinetics
openaire   +2 more sources