Results 241 to 250 of about 2,634,573 (271)
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Models of Genetic Recombination
Annual Review of Microbiology, 1974It will be my intention to compare established and recently proposed models for . genetic recombination, with special attention to the separate component principles they contain and the function ofthese principles in the various models. As increasing attention has been paid to realistic details of DNA structure and enzymology, recombination models have
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Genetic models of schizophrenia
Acta Psychiatrica Scandinavica, 1982Multiple threshold models of inheritance are applied to a large sample of Franz Kallmann's (1938) pedigree data on schizophrenia. Paranoid and nonparanoid subtypes are represented in the models at different thresholds on a continuum of genetic‐environmental liability. Single major locus and multifactorial‐polygenic inheritance are ruled out as modes of
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Some Models of Genetic Selection
Biometrics, 1979This paper begins with a description of the classical theory of viability selection in which probabilities that individuals of various genotypes survive are in proportions that do not change with time and are independent of population structure. Salient features of viability selection with one and two loci are reviewed.
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2009
Abstract The “Fisherian” optimality approach determines the optimal combination of trait values but not the evolutionary trajectory nor, in general, the variation to be expected about the optimal combination. Invasibility analysis is also primarily concerned with the Evolutionarily Stable Strategy (ESS) values; though assuming clonal ...
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Abstract The “Fisherian” optimality approach determines the optimal combination of trait values but not the evolutionary trajectory nor, in general, the variation to be expected about the optimal combination. Invasibility analysis is also primarily concerned with the Evolutionarily Stable Strategy (ESS) values; though assuming clonal ...
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1992
Abstract Certain features of the epidemiology of neural tube defects are consistent with a genetic component in their aetiology. First, concordance rates for neural tube defects are significantly higher in twin pairs of like sex than in twin pairs of unlike sex (Chapter 11). Thus, it is likely that monozygotic twins are concordant for
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Abstract Certain features of the epidemiology of neural tube defects are consistent with a genetic component in their aetiology. First, concordance rates for neural tube defects are significantly higher in twin pairs of like sex than in twin pairs of unlike sex (Chapter 11). Thus, it is likely that monozygotic twins are concordant for
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Genetic Programming in Economic Modelling
2005 IEEE Congress on Evolutionary Computation, 2005Typically, economists develop models by first selecting a model structure based on theoretical considerations and equilibrium conditions, followed by parameter estimation from available data. As more and more data become available about economic processes, the question arises whether it is possible to obtain models in which "data speak for themselves",
Duyvesteyn, K., Kaymak, U.
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Genetic models of reading disability
Behavior Genetics, 1980Test data collected on 133 reading-disabled (RD) children and their nuclear families who participated in the Colorado Family Reading Study were subjected to segregation analysis utilizing the technique of Elston and Yelverton (1975) for a continuous phenotypic measure.
F I, Lewitter, J C, DeFries, R C, Elston
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2003
Genetics is the study of heredity and variation among organisms. It is known that in all living organisms, reproduction involves the passing from one generation to the next a genetic code that determines all physical aspects of the offspring. This code is carried on chromosomes. Chromosomes are large molecules in living cells that carry the information
Anatoly Swishchuk, Jianhong Wu
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Genetics is the study of heredity and variation among organisms. It is known that in all living organisms, reproduction involves the passing from one generation to the next a genetic code that determines all physical aspects of the offspring. This code is carried on chromosomes. Chromosomes are large molecules in living cells that carry the information
Anatoly Swishchuk, Jianhong Wu
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2014
Genetic animal models have a long history of contribution to the understanding of alcohol dependence. Studies have provided insight into genetic contributions to risk and are beginning to be used to suggest better targeted pharmacotherapies. This review discusses how different species and genetic methods have been used to target specific aspects of ...
John C. Crabbe, Tamara J. Phillips
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Genetic animal models have a long history of contribution to the understanding of alcohol dependence. Studies have provided insight into genetic contributions to risk and are beginning to be used to suggest better targeted pharmacotherapies. This review discusses how different species and genetic methods have been used to target specific aspects of ...
John C. Crabbe, Tamara J. Phillips
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Modeling RASopathies with Genetically Modified Mouse Models
2016The RAS/MAPK signaling pathway plays key roles in development, cell survival and proliferation, as well as in cancer pathogenesis. Molecular genetic studies have identified a group of developmental syndromes, the RASopathies, caused by germ line mutations in this pathway.
Isabel, Hernández-Porras +1 more
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