Results 91 to 100 of about 11,616,863 (296)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Skeletal dysmorphology and mineralization defects in Fgf20 KO mice
Frontiers in EndocrinologyIntroductionFibroblast growth factor 20 (Fgf20), a member of the Fgf9 subfamily, was identified as an important regulator of bone differentiation and homeostasis processes. However, the role of Fgf20 in bone physiology has not been approached yet.
Sylvie Dlugosova +11 more
doaj +1 more source
Novel Solubility Prediction Models: Molecular Fingerprints and Physicochemical Features vs Graph Convolutional Neural Networks. [PDF]
ACS Omega, 2022 Lee S +5 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Folder 6: Model engine data sheets and operating instructions, J - N, ca. 1960, 1972, 1988
, 1960 Instructions, illustrations, and parts price list for a Dynamic Models, INC. Johnson Engines.
Dynamic Models, Inc.
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
BMC GenomicsBackground Structural variations (SVs) are widespread across genome and have a great impact on evolution, disease, and phenotypic diversity. Despite the development of numerous bioinformatic tools, commonly referred to as SV callers, tailored for ...
Cheng Ma +4 more
doaj +1 more source
Molecular modelling of fentanyl analogs
Journal of the Serbian Chemical Society, 2004 Fentanyl is a highly potent and clinically widely used narcotic analgesic. A large number of its analogs have been synthesized, some of which (sufentanil and alfentanyl) are also in clinical use. Theoretical studies, in recent years, afforded a better understanding of the structure-activity relationships of this class of opiates and allowed insight ...
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Newsletter Institute of Medical Molecular Biotechnology Issue 14 Disember 2021 / Institute of Medical Molecular Biotechnology [PDF]
, 2021 The Institute of Medical Molecular Biotechnology (IMMB) at Universiti Teknologi MARA (UiTM) launched its inaugural newsletter in November 2020. This publication serves as a platform to disseminate the institute's latest research activities, events, and ...
Universiti Teknologi MARA, Institute of Medical Molecular Biotechnology
core